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Gene: Angpt1 (angiopoietin 1) Mus musculus
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Symbol: Angpt1
Name: angiopoietin 1
Description: Exhibits signaling receptor binding activity. Involved in several processes, including negative regulation of protein transport; regulation of protein phosphorylation; and regulation of signal transduction. Predicted to localize to several cellular components, including the extracellular space; membrane raft; and microvillus. Human ortholog(s) of this gene implicated in brain ischemia; diabetic retinopathy; and hypertension. Is expressed in several structures, including cardiovascular system; liver; lung; metanephros; and yolk sac. Orthologous to human ANGPT1 (angiopoietin 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 1110046O21Rik; Ang-1; Ang1; angiopoietin-1
Orthologs:
Homo sapiens (human) : ANGPT1 (angiopoietin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Angpt1 (angiopoietin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Angpt1 (angiopoietin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ANGPT1 (angiopoietin 1)
Canis lupus familiaris (dog) : ANGPT1 (angiopoietin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Angpt1 (angiopoietin 1)
Sus scrofa (pig) : ANGPT1 (angiopoietin 1)
Chlorocebus sabaeus (African green monkey) : ANGPT1 (angiopoietin 1)
Heterocephalus glaber (naked mole-rat) : Angpt1 (angiopoietin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1542,424,723 - 42,676,977 (-)Ensembl
GRCm381542,424,667 - 42,676,977 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371542,256,269 - 42,508,341 (-)NCBIGRCm37mm9NCBIm37
MGSCv361542,254,797 - 42,506,869 (-)NCBImm8
Celera1542,923,745 - 43,172,815 (-)NCBICelera
Cytogenetic Map15 B3.1NCBI
cM Map1516.69NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Angpt1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551549
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-01-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.