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Gene: Gchfr (GTP cyclohydrolase I feedback regulator) Mus musculus
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Symbol: Gchfr
Name: GTP cyclohydrolase I feedback regulator
Description: Predicted to have several functions, including GTP cyclohydrolase binding activity; GTP-dependent protein binding activity; and amino acid binding activity. Predicted to be involved in negative regulation of GTP cyclohydrolase I activity and protein heterooligomerization. Predicted to localize to several cellular components, including the dendrite; melanosome; and nucleus. Is expressed in medulla oblongata basal plate marginal layer; midbrain mantle layer; and pons marginal layer. Orthologous to human GCHFR (GTP cyclohydrolase I feedback regulator); PARTICIPATES IN dopa responsive dystonia pathway; Segawa syndrome pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-diaminotoluene; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 2010323F13Rik; GFRP; GTP cyclohydrolase 1 feedback regulatory protein; GTP cyclohydrolase I feedback regulatory protein; P35
Orthologs:
Homo sapiens (human) : GCHFR (GTP cyclohydrolase I feedback regulator)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gchfr (GTP cyclohydrolase I feedback regulator)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gchfr (GTP cyclohydrolase I feedback regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : GCHFR (GTP cyclohydrolase I feedback regulator)
Canis lupus familiaris (dog) : GCHFR (GTP cyclohydrolase I feedback regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gchfr (GTP cyclohydrolase I feedback regulator)
Sus scrofa (pig) : GCHFR (GTP cyclohydrolase I feedback regulator)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm382119,167,788 - 119,172,389 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372118,993,524 - 118,998,125 (+)NCBIGRCm37mm9NCBIm37
MGSCv362118,859,229 - 118,863,830 (+)NCBImm8
Celera2120,318,697 - 120,323,019 (+)NCBICelera
Cytogenetic Map2 E5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Gchfr
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551561
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.