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Gene: Crbn (cereblon) Mus musculus
Symbol: Crbn
Name: cereblon
Description: Predicted to have metal ion binding activity. Predicted to be involved in several processes, including cellular protein metabolic process; negative regulation of protein homooligomerization; and positive regulation of protein homodimerization activity. Predicted to localize to the Cul4A-RING E3 ubiquitin ligase complex; cytoplasm; and nucleus. Used to study autosomal recessive non-syndromic intellectual disability. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Is expressed in several structures, including alimentary system; aorta; central nervous system; eye; and genitourinary system. Orthologous to human CRBN (cereblon).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2610203G15Rik; 2900045O07Rik; AF229032; AW108261; novel lethal; piL; RIKEN cDNA 2900045O07 gene
Homo sapiens (human) : CRBN (cereblon)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Crbn (cereblon)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Crbn (cereblon)
Pan paniscus (bonobo/pygmy chimpanzee) : CRBN (cereblon)
Canis lupus familiaris (dog) : CRBN (cereblon)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Crbn (cereblon)
Sus scrofa (pig) : CRBN (cereblon)
Chlorocebus sabaeus (green monkey) : CRBN (cereblon)
Heterocephalus glaber (naked mole-rat) : Crbn (cereblon)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl6106,780,201 - 106,800,077 (-)Ensembl
GRCm386106,778,244 - 106,800,099 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376106,728,238 - 106,750,068 (-)NCBIGRCm37mm9NCBIm37
MGSCv366106,744,026 - 106,765,846 (-)NCBImm8
Celera6108,595,522 - 108,617,365 (-)NCBICelera
Cytogenetic Map6 E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Crbn
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551562
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.