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Gene: Ano1 (anoctamin 1, calcium activated chloride channel) Mus musculus
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Symbol: Ano1
Name: anoctamin 1, calcium activated chloride channel
Description: Exhibits chloride channel activity and protein dimerization activity. Involved in several processes, including detection of temperature stimulus involved in sensory perception of pain; positive regulation of insulin secretion involved in cellular response to glucose stimulus; and trachea development. Localizes to the apical plasma membrane; external side of plasma membrane; and integral component of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human ANO1 (anoctamin 1); INTERACTS WITH (-)-epigallocatechin 3-gallate; 17alpha-ethynylestradiol; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: anoctamin-1; AU040576; AW559012; Tmem16a; transmembrane protein 16A
Orthologs:
Homo sapiens (human) : ANO1 (anoctamin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ano1 (anoctamin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ano1 (anoctamin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ANO1 (anoctamin 1)
Canis lupus familiaris (dog) : ANO1 (anoctamin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ano1 (anoctamin 1)
Sus scrofa (pig) : ANO1 (anoctamin 1)
Chlorocebus sabaeus (African green monkey) : ANO1 (anoctamin 1)
Heterocephalus glaber (naked mole-rat) : Ano1 (anoctamin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl7144,588,549 - 144,751,974 (-)Ensembl
GRCm387144,588,549 - 144,752,026 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377151,774,550 - 151,924,383 (-)NCBIGRCm37mm9NCBIm37
MGSCv367144,398,033 - 144,547,933 (-)NCBImm8
Celera7144,352,388 - 144,502,919 (-)NCBICelera
Cytogenetic Map7 F5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ano1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551631
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-01-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.