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Gene: Ano1 (anoctamin 1, calcium activated chloride channel) Mus musculus
Symbol: Ano1
Name: anoctamin 1, calcium activated chloride channel
Description: Exhibits chloride channel activity and protein dimerization activity. Involved in several processes, including detection of temperature stimulus involved in sensory perception of pain; positive regulation of insulin secretion involved in cellular response to glucose stimulus; and trachea development. Localizes to the apical plasma membrane; external side of plasma membrane; and integral component of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human ANO1 (anoctamin 1); INTERACTS WITH (-)-epigallocatechin 3-gallate; 17alpha-ethynylestradiol; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: anoctamin-1; AU040576; AW559012; Tmem16a; transmembrane protein 16A
Homo sapiens (human) : ANO1 (anoctamin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ano1 (anoctamin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ano1 (anoctamin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ANO1 (anoctamin 1)
Canis lupus familiaris (dog) : ANO1 (anoctamin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ano1 (anoctamin 1)
Sus scrofa (pig) : ANO1 (anoctamin 1)
Chlorocebus sabaeus (African green monkey) : ANO1 (anoctamin 1)
Heterocephalus glaber (naked mole-rat) : Ano1 (anoctamin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl7144,588,549 - 144,751,974 (-)Ensembl
GRCm387144,588,549 - 144,752,026 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377151,774,550 - 151,924,383 (-)NCBIGRCm37mm9NCBIm37
MGSCv367144,398,033 - 144,547,933 (-)NCBImm8
Celera7144,352,388 - 144,502,919 (-)NCBICelera
Cytogenetic Map7 F5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ano1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551631
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-01-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.