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Gene: Nfya (nuclear transcription factor-Y alpha) Mus musculus
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Symbol: Nfya
Name: nuclear transcription factor-Y alpha
CRRD ID: 1551652
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Contributes to transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of stem cell proliferation; positive regulation of transcription by RNA polymerase II; and regulation of stem cell population maintenance. Localizes to nucleus. Is expressed in several structures, including branchial arch; cerebral cortex; early conceptus; genitourinary system; and hemolymphoid system gland. Orthologous to human NFYA (nuclear transcription factor Y subunit alpha); PARTICIPATES IN altered p53 signaling pathway; antigen processing and presentation pathway; tuberculosis pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA407810; CAAT box DNA-binding protein subunit A; CAAT-box DNA-binding protein subunit A; Cbf-b; NF-YA; nuclear transcription factor Y subunit A; nuclear transcription factor Y subunit alpha; SEZ-10; Sez1; SEZ10
Orthologs:
Homo sapiens (human) : NFYA (nuclear transcription factor Y subunit alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nfya (nuclear transcription factor Y subunit alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfya (nuclear transcription factor Y subunit alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : NFYA (nuclear transcription factor Y subunit alpha)
Canis lupus familiaris (dog) : NFYA (nuclear transcription factor Y subunit alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfya (nuclear transcription factor Y subunit alpha)
Sus scrofa (pig) : NFYA (nuclear transcription factor Y subunit alpha)
Chlorocebus sabaeus (African green monkey) : NFYA (nuclear transcription factor Y subunit alpha)
Heterocephalus glaber (naked mole-rat) : Nfya (nuclear transcription factor Y subunit alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391748,693,913 - 48,716,848 (-)NCBI
GRCm381748,386,885 - 48,409,820 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1748,386,885 - 48,409,906 (-)EnsemblGRCm38mm10GRCm38
MGSCv371748,526,210 - 48,549,145 (-)NCBIGRCm37mm9NCBIm37
MGSCv361747,853,500 - 47,875,288 (-)NCBImm8
Celera1751,818,370 - 51,841,444 (-)NCBICelera
Cytogenetic Map17CNCBI
cM Map1723.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Nfya
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551652
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.