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Gene: Trpm4 (transient receptor potential cation channel, subfamily M, member 4) Mus musculus
Symbol: Trpm4
Name: transient receptor potential cation channel, subfamily M, member 4
CRRD ID: 1551863
Description: Exhibits ATP binding activity; calcium activated cation channel activity; and calcium channel activity. Involved in several processes, including cation transport; cellular response to ATP; and protein homotetramerization. Localizes to spanning component of plasma membrane. Is expressed in brain; cochlea; dorsal root ganglion; inferior vagus ganglion; and vagus ganglion. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis and progressive familial heart block type IB. Orthologous to human TRPM4 (transient receptor potential cation channel subfamily M member 4); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110030C19Rik; AW047689; calcium-activated non-selective cation channel 1; FLJ20041; long transient receptor potential channel 4; LTR; LTrpC-4; LTRPC4; transient receptor potential cation channel subfamily M member 4; transient receptor potential ion channel melastatin subgroup member 4; TRPM; TRPM4B
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl745,302,632 - 45,333,780 (-)EnsemblGRCm38mm10GRCm38
GRCm38745,303,155 - 45,334,071 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37752,558,525 - 52,589,150 (-)NCBIGRCm37mm9NCBIm37
MGSCv36745,170,674 - 45,201,784 (-)NCBImm8
Celera740,759,067 - 40,790,038 (-)NCBICelera
Cytogenetic Map7B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Trpm4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551863
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.