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Gene: Cav2 (caveolin 2) Mus musculus
Symbol: Cav2
Name: caveolin 2
CRRD ID: 1551950
Description: Exhibits several functions, including protein heterodimerization activity; protein kinase binding activity; and scaffold protein binding activity. Involved in several processes, including negative regulation of transforming growth factor beta receptor signaling pathway; regulation of endothelial cell proliferation; and skeletal muscle fiber development. Localizes to acrosomal membrane and caveolar macromolecular signaling complex. Colocalizes with focal adhesion. Is expressed in bronchiole epithelium; embryo; and lung. Human ortholog(s) of this gene implicated in low tension glaucoma and primary open angle glaucoma. Orthologous to human CAV2 (caveolin 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI447843; caveolin-2
Homo sapiens (human) : CAV2 (caveolin 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cav2 (caveolin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cav2 (caveolin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CAV2 (caveolin 2)
Canis lupus familiaris (dog) : CAV2 (caveolin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cav2 (caveolin 2)
Sus scrofa (pig) : CAV2 (caveolin 2)
Chlorocebus sabaeus (African green monkey) : CAV2 (caveolin 2)
Heterocephalus glaber (naked mole-rat) : Cav2 (caveolin 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39617,281,184 - 17,289,129 (+)NCBI
GRCm38617,281,185 - 17,289,130 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl617,281,185 - 17,289,115 (+)EnsemblGRCm38mm10GRCm38
MGSCv37617,231,341 - 17,239,011 (+)NCBIGRCm37mm9NCBIm37
MGSCv36617,231,341 - 17,239,011 (+)NCBImm8
Celera617,353,818 - 17,361,488 (+)NCBICelera
Cytogenetic Map6A2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cav2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551950
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.