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Gene: Cav2 (caveolin 2) Mus musculus
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Symbol: Cav2
Name: caveolin 2
CRRD ID: 1551950
Description: Exhibits several functions, including protein heterodimerization activity; protein kinase binding activity; and scaffold protein binding activity. Involved in several processes, including negative regulation of transforming growth factor beta receptor signaling pathway; regulation of endothelial cell proliferation; and skeletal muscle fiber development. Localizes to acrosomal membrane and caveolar macromolecular signaling complex. Colocalizes with focal adhesion. Is expressed in bronchiole epithelium; embryo; and lung. Human ortholog(s) of this gene implicated in low tension glaucoma and primary open angle glaucoma. Orthologous to human CAV2 (caveolin 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI447843; caveolin-2
Orthologs:
Homo sapiens (human) : CAV2 (caveolin 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cav2 (caveolin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cav2 (caveolin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CAV2 (caveolin 2)
Canis lupus familiaris (dog) : CAV2 (caveolin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cav2 (caveolin 2)
Sus scrofa (pig) : CAV2 (caveolin 2)
Chlorocebus sabaeus (African green monkey) : CAV2 (caveolin 2)
Heterocephalus glaber (naked mole-rat) : Cav2 (caveolin 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39617,281,184 - 17,289,129 (+)NCBI
GRCm38617,281,185 - 17,289,130 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl617,281,185 - 17,289,115 (+)EnsemblGRCm38mm10GRCm38
MGSCv37617,231,341 - 17,239,011 (+)NCBIGRCm37mm9NCBIm37
MGSCv36617,231,341 - 17,239,011 (+)NCBImm8
Celera617,353,818 - 17,361,488 (+)NCBICelera
Cytogenetic Map6A2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cav2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551950
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.