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Gene: Grm4 (glutamate receptor, metabotropic 4) Mus musculus
Symbol: Grm4
Name: glutamate receptor, metabotropic 4
CRRD ID: 1551969
Description: Predicted to have calcium-dependent protein binding activity; calmodulin binding activity; and group III metabotropic glutamate receptor activity. Involved in chemical synaptic transmission; learning; and regulation of synaptic vesicle exocytosis. Localizes to several cellular components, including glutamatergic synapse; integral component of presynaptic active zone membrane; and parallel fiber to Purkinje cell synapse. Is expressed in central nervous system; dorsal root ganglion; foot; sensory organ; and skeleton. Orthologous to human GRM4 (glutamate metabotropic receptor 4); PARTICIPATES IN glutamate signaling pathway; INTERACTS WITH 1,2-dichloroethane; 4,4'-sulfonyldiphenol; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: G protein-coupled receptor GRM4; G protein-coupled receptor, family C, group 1, member D; Gprc; Gprc1d; metabotropic glutamate receptor 4; mGlu; mGluR4
Homo sapiens (human) : GRM4 (glutamate metabotropic receptor 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Grm4 (glutamate metabotropic receptor 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grm4 (glutamate metabotropic receptor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : GRM4 (glutamate metabotropic receptor 4)
Canis lupus familiaris (dog) : GRM4 (glutamate metabotropic receptor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grm4 (glutamate metabotropic receptor 4)
Sus scrofa (pig) : GRM4 (glutamate metabotropic receptor 4)
Heterocephalus glaber (naked mole-rat) : Grm4 (glutamate metabotropic receptor 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391727,641,361 - 27,732,800 (-)NCBI
GRCm381727,422,387 - 27,513,826 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1727,422,387 - 27,521,403 (-)EnsemblGRCm38mm10GRCm38
MGSCv371727,559,332 - 27,640,249 (-)NCBIGRCm37mm9NCBIm37
MGSCv361727,149,976 - 27,230,893 (-)NCBImm8
Celera1727,978,671 - 28,055,379 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Grm4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551969
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-11-03
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.