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Gene: Odc1 (ornithine decarboxylase, structural 1) Mus musculus
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Symbol: Odc1
Name: ornithine decarboxylase, structural 1
Description: Exhibits ornithine decarboxylase activity and protein homodimerization activity. Involved in several processes, including positive regulation of cell population proliferation; putrescine biosynthetic process from ornithine; and regulation of protein catabolic process. Localizes to cytosol. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Used to study atrichia with papular lesions. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human ODC1 (ornithine decarboxylase 1); PARTICIPATES IN biogenic amines and polyamines metabolic pathway; polyamine metabolic pathway; putrescine metabolic pathway; INTERACTS WITH (+)-catechin; (S)-(-)-perillyl alcohol; (S)-colchicine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC103389; ODC; ornithine decarboxylase
Orthologs:
Homo sapiens (human) : ODC1 (ornithine decarboxylase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Odc1 (ornithine decarboxylase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Odc1 (ornithine decarboxylase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ODC1 (ornithine decarboxylase 1)
Canis lupus familiaris (dog) : ODC1 (ornithine decarboxylase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Odc1 (ornithine decarboxylase 1)
Sus scrofa (pig) : ODC1 (ornithine decarboxylase 1)
Chlorocebus sabaeus (African green monkey) : ODC1 (ornithine decarboxylase 1)
Heterocephalus glaber (naked mole-rat) : Odc1 (ornithine decarboxylase 1)
more info ...
Related Pseudogenes: Gm12846   Gm14785   Gm15470   Gm15645   Gm17709   Gm7278   Gm7450   Gm7993   Gm8828   Gm8836   Gm8848   Gm8853   Gm8862   Gm8872   Gm8982   Gm9115   Gm9260   Rps7-ps2  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1217,544,794 - 17,551,505 (+)EnsemblGRCm38mm10GRCm38
GRCm381217,544,808 - 17,551,502 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371217,551,679 - 17,558,308 (+)NCBIGRCm37mm9NCBIm37
MGSCv361217,570,570 - 17,576,557 (+)NCBImm8
Celera1217,867,446 - 17,874,062 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map128.11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on Odc1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1551973
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.