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Gene: Cx3cr1 (chemokine (C-X3-C motif) receptor 1) Mus musculus
Symbol: Cx3cr1
Name: chemokine (C-X3-C motif) receptor 1
Description: Exhibits C-X3-C chemokine binding activity; G protein-coupled receptor activity; and cytokine receptor activity. Involved in several processes, including leukocyte migration; nervous system development; and regulation of cellular biosynthetic process. Localizes to cell surface. Is expressed in several structures, including colon; genitourinary system; and liver. Used to study age related macular degeneration 12. Human ortholog(s) of this gene implicated in several diseases, including human immunodeficiency virus infectious disease; obesity; pulmonary hypertension; retinal disease (multiple); and systemic scleroderma. Orthologous to human CX3CR1 (C-X3-C motif chemokine receptor 1); INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C-X3-C chemokine receptor 1; C-X3-C CKR-1; chemokine (C-X3-C) receptor 1; CX3C chemokine receptor 1; fractalkine receptor
Homo sapiens (human) : CX3CR1 (C-X3-C motif chemokine receptor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cx3cr1 (C-X3-C motif chemokine receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cx3cr1 (C-X3-C motif chemokine receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CX3CR1 (C-X3-C motif chemokine receptor 1)
Canis lupus familiaris (dog) : CX3CR1 (C-X3-C motif chemokine receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cx3cr1 (C-X3-C motif chemokine receptor 1)
Sus scrofa (pig) : CX3CR1 (C-X3-C motif chemokine receptor 1)
Chlorocebus sabaeus (African green monkey) : CX3CR1 (C-X3-C motif chemokine receptor 1)
Heterocephalus glaber (naked mole-rat) : Cx3cr1 (C-X3-C motif chemokine receptor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl9119,901,616 - 120,069,879 (-)EnsemblGRCm38mm10GRCm38
GRCm389120,048,683 - 120,068,296 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379119,957,811 - 119,977,400 (-)NCBIGRCm37mm9NCBIm37
MGSCv369119,897,391 - 119,916,980 (-)NCBImm8
Celera9120,518,248 - 120,537,939 (-)NCBICelera
Cytogenetic Map9F4NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Cx3cr1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552004
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.