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Gene: Dag1 (dystroglycan 1) Mus musculus
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Symbol: Dag1
Name: dystroglycan 1
Description: Exhibits dystroglycan binding activity. Involved in several processes, including morphogenesis of an epithelium; nervous system development; and retrograde trans-synaptic signaling by trans-synaptic protein complex. Localizes to several cellular components, including the dystroglycan complex; node of Ranvier; and sarcolemma. Predicted to colocalize with the focal adhesion. Used to study autosomal recessive limb-girdle muscular dystrophy type 2P; dilated cardiomyopathy; and lissencephaly. Human ortholog(s) of this gene implicated in Duchenne muscular dystrophy; autosomal recessive limb-girdle muscular dystrophy type 2D; autosomal recessive limb-girdle muscular dystrophy type 2P; congenital muscular dystrophy-dystroglycanopathy type A9; and inclusion body myositis. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and musculature. Orthologous to human DAG1 (dystroglycan 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha-dystroglycan; beta-dystroglycan; D9Wsu13e; DG; Dp427; Dp71; dystroglycan; dystrophin associated glycoprotein 1; dystrophin-associated glycoprotein 1
Orthologs:
Homo sapiens (human) : DAG1 (dystroglycan 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dag1 (dystroglycan 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dag1 (dystroglycan 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DAG1 (dystroglycan 1)
Canis lupus familiaris (dog) : DAG1 (dystroglycan 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dag1 (dystroglycan 1)
Sus scrofa (pig) : DAG1 (dystroglycan 1)
Chlorocebus sabaeus (green monkey) : DAG1 (dystroglycan 1)
Heterocephalus glaber (naked mole-rat) : Dag1 (dystroglycan 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl9108,204,634 - 108,263,958 (-)Ensembl
GRCm389108,204,861 - 108,263,977 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379108,108,289 - 108,166,067 (-)NCBIGRCm37mm9NCBIm37
MGSCv369108,064,059 - 108,121,837 (-)NCBImm8
Celera9107,813,482 - 107,872,794 (-)NCBICelera
Cytogenetic Map9 F1NCBI
cM Map959.08NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Dag1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552006
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-02-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.