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Gene: Dag1 (dystroglycan 1) Mus musculus
Symbol: Dag1
Name: dystroglycan 1
Description: Exhibits dystroglycan binding activity. Involved in several processes, including morphogenesis of an epithelium; nervous system development; and retrograde trans-synaptic signaling by trans-synaptic protein complex. Localizes to several cellular components, including the dystroglycan complex; node of Ranvier; and sarcolemma. Predicted to colocalize with the focal adhesion. Used to study autosomal recessive limb-girdle muscular dystrophy type 2P; dilated cardiomyopathy; and lissencephaly. Human ortholog(s) of this gene implicated in Duchenne muscular dystrophy; autosomal recessive limb-girdle muscular dystrophy type 2D; autosomal recessive limb-girdle muscular dystrophy type 2P; congenital muscular dystrophy-dystroglycanopathy type A9; and inclusion body myositis. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and musculature. Orthologous to human DAG1 (dystroglycan 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha-dystroglycan; beta-dystroglycan; D9Wsu13e; DG; Dp427; Dp71; dystroglycan; dystrophin associated glycoprotein 1; dystrophin-associated glycoprotein 1
Homo sapiens (human) : DAG1 (dystroglycan 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dag1 (dystroglycan 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dag1 (dystroglycan 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DAG1 (dystroglycan 1)
Canis lupus familiaris (dog) : DAG1 (dystroglycan 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dag1 (dystroglycan 1)
Sus scrofa (pig) : DAG1 (dystroglycan 1)
Chlorocebus sabaeus (green monkey) : DAG1 (dystroglycan 1)
Heterocephalus glaber (naked mole-rat) : Dag1 (dystroglycan 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl9108,204,634 - 108,263,958 (-)Ensembl
GRCm389108,204,861 - 108,263,977 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379108,108,289 - 108,166,067 (-)NCBIGRCm37mm9NCBIm37
MGSCv369108,064,059 - 108,121,837 (-)NCBImm8
Celera9107,813,482 - 107,872,794 (-)NCBICelera
Cytogenetic Map9 F1NCBI
cM Map959.08NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Dag1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552006
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-02-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.