Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Smyd2 (SET and MYND domain containing 2) Mus musculus
Analyze
Symbol: Smyd2
Name: SET and MYND domain containing 2
CRRD ID: 1552013
Description: Exhibits RNA polymerase II complex binding activity and histone methyltransferase activity (H3-K36 specific). Involved in histone methylation; negative regulation of cell population proliferation; and peptidyl-lysine dimethylation. Localizes to cytosol and nucleus. Is expressed in several structures, including heart; hemolymphoid system gland; nasal cavity epithelium; nervous system; and retina. Orthologous to human SMYD2 (SET and MYND domain containing 2); PARTICIPATES IN histone modification pathway; methionine cycle/metabolic pathway; p53 signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 5-aza-2'-deoxycytidine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110020E07Rik; 4930402C15; histone methyltransferase SMYD2; KMT3C; N-lysine methyltransferase SMYD2; SET and MYND domain-containing protein 2; Zmynd1; Zmynd14
Orthologs:
Homo sapiens (human) : SMYD2 (SET and MYND domain containing 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Smyd2 (SET and MYND domain containing 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smyd2 (SET and MYND domain containing 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SMYD2 (SET and MYND domain containing 2)
Canis lupus familiaris (dog) : SMYD2 (SET and MYND domain containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smyd2 (SET and MYND domain containing 2)
Sus scrofa (pig) : SMYD2 (SET and MYND domain containing 2)
Chlorocebus sabaeus (African green monkey) : SMYD2 (SET and MYND domain containing 2)
Heterocephalus glaber (naked mole-rat) : Smyd2 (SET and MYND domain containing 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1189,880,492 - 189,922,363 (-)EnsemblGRCm38mm10GRCm38
GRCm381189,880,492 - 189,922,495 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371191,704,371 - 191,746,167 (-)NCBIGRCm37mm9NCBIm37
MGSCv361191,581,280 - 191,623,076 (-)NCBImm8
Celera1196,790,858 - 196,832,656 (-)NCBICelera
Cytogenetic Map1H6NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Smyd2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552013
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.