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Gene: Smyd2 (SET and MYND domain containing 2) Mus musculus
Symbol: Smyd2
Name: SET and MYND domain containing 2
CRRD ID: 1552013
Description: Exhibits RNA polymerase II complex binding activity and histone methyltransferase activity (H3-K36 specific). Involved in histone methylation; negative regulation of cell population proliferation; and peptidyl-lysine dimethylation. Localizes to cytosol and nucleus. Is expressed in several structures, including heart; hemolymphoid system gland; nasal cavity epithelium; nervous system; and retina. Orthologous to human SMYD2 (SET and MYND domain containing 2); PARTICIPATES IN histone modification pathway; methionine cycle/metabolic pathway; p53 signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 5-aza-2'-deoxycytidine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110020E07Rik; 4930402C15; histone methyltransferase SMYD2; KMT3C; N-lysine methyltransferase SMYD2; SET and MYND domain-containing protein 2; Zmynd1; Zmynd14
Homo sapiens (human) : SMYD2 (SET and MYND domain containing 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Smyd2 (SET and MYND domain containing 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smyd2 (SET and MYND domain containing 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SMYD2 (SET and MYND domain containing 2)
Canis lupus familiaris (dog) : SMYD2 (SET and MYND domain containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smyd2 (SET and MYND domain containing 2)
Sus scrofa (pig) : SMYD2 (SET and MYND domain containing 2)
Chlorocebus sabaeus (African green monkey) : SMYD2 (SET and MYND domain containing 2)
Heterocephalus glaber (naked mole-rat) : Smyd2 (SET and MYND domain containing 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1189,880,492 - 189,922,363 (-)EnsemblGRCm38mm10GRCm38
GRCm381189,880,492 - 189,922,495 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371191,704,371 - 191,746,167 (-)NCBIGRCm37mm9NCBIm37
MGSCv361191,581,280 - 191,623,076 (-)NCBImm8
Celera1196,790,858 - 196,832,656 (-)NCBICelera
Cytogenetic Map1H6NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Smyd2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552013
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.