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Gene: Ccr2 (chemokine (C-C motif) receptor 2) Mus musculus
Symbol: Ccr2
Name: chemokine (C-C motif) receptor 2
Description: Exhibits C-C chemokine binding activity and C-C chemokine receptor activity. Involved in several processes, including leukocyte migration; positive regulation of cell migration; and regulation of cytokine production. Localizes to external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Used to study age related macular degeneration. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; aggressive periodontitis; coronary artery disease (multiple); diabetes mellitus (multiple); and uveitis (multiple). Orthologous to human CCR2 (C-C motif chemokine receptor 2); INTERACTS WITH (+)-catechin; (+)-pilocarpine; 1-chloro-2,4-dinitrobenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C-C chemokine receptor type 2; C-C CHEMOKINE RECEPTOR TYPE 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC RECEPTOR) (MCP-1 RECEPTOR); C-C CKR-2; Cc-ckr-2; CCR-2; Ccr2a; Ccr2b; chemoattractant protein-1 receptor; chemokine (C-C) receptor 2; Ckr2; Ckr2a; Ckr2b; Cmkbr2; JE/FIC receptor; MCP-1 receptor; MIP-1 alphaR; mJe-r
Homo sapiens (human) : CCR2 (C-C motif chemokine receptor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ccr2 (C-C motif chemokine receptor 2)
Chinchilla lanigera (long-tailed chinchilla) : Ccr2 (C-C motif chemokine receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CCR2 (C-C motif chemokine receptor 2)
Canis lupus familiaris (dog) : CCR2 (C-C motif chemokine receptor 2)
Sus scrofa (pig) : CCR2 (C-C motif chemokine receptor 2)
Chlorocebus sabaeus (African green monkey) : CCR2 (C-C motif chemokine receptor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl9124,101,950 - 124,113,557 (+)EnsemblGRCm38mm10GRCm38
GRCm389124,101,918 - 124,109,140 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379124,016,922 - 124,023,879 (+)NCBIGRCm37mm9NCBIm37
MGSCv369123,950,982 - 123,957,349 (+)NCBImm8
Celera9124,890,502 - 124,897,441 (-)NCBICelera
Cytogenetic Map9F4NCBI
cM Map975.05NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ccr2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552061
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.