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Gene: Ccr2 (chemokine (C-C motif) receptor 2) Mus musculus
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Symbol: Ccr2
Name: chemokine (C-C motif) receptor 2
Description: Exhibits C-C chemokine binding activity and C-C chemokine receptor activity. Involved in several processes, including leukocyte migration; positive regulation of cell migration; and regulation of cytokine production. Localizes to external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Used to study age related macular degeneration. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; aggressive periodontitis; coronary artery disease (multiple); diabetes mellitus (multiple); and uveitis (multiple). Orthologous to human CCR2 (C-C motif chemokine receptor 2); INTERACTS WITH (+)-catechin; (+)-pilocarpine; 1-chloro-2,4-dinitrobenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C-C chemokine receptor type 2; C-C CHEMOKINE RECEPTOR TYPE 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC RECEPTOR) (MCP-1 RECEPTOR); C-C CKR-2; Cc-ckr-2; CCR-2; Ccr2a; Ccr2b; chemoattractant protein-1 receptor; chemokine (C-C) receptor 2; Ckr2; Ckr2a; Ckr2b; Cmkbr2; JE/FIC receptor; MCP-1 receptor; MIP-1 alphaR; mJe-r
Orthologs:
Homo sapiens (human) : CCR2 (C-C motif chemokine receptor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ccr2 (C-C motif chemokine receptor 2)
Chinchilla lanigera (long-tailed chinchilla) : Ccr2 (C-C motif chemokine receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CCR2 (C-C motif chemokine receptor 2)
Canis lupus familiaris (dog) : CCR2 (C-C motif chemokine receptor 2)
Sus scrofa (pig) : CCR2 (C-C motif chemokine receptor 2)
Chlorocebus sabaeus (African green monkey) : CCR2 (C-C motif chemokine receptor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl9124,101,950 - 124,113,557 (+)EnsemblGRCm38mm10GRCm38
GRCm389124,101,918 - 124,109,140 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379124,016,922 - 124,023,879 (+)NCBIGRCm37mm9NCBIm37
MGSCv369123,950,982 - 123,957,349 (+)NCBImm8
Celera9124,890,502 - 124,897,441 (-)NCBICelera
Cytogenetic Map9F4NCBI
cM Map975.05NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ccr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552061
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.