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Gene: Dnmt1 (DNA methyltransferase (cytosine-5) 1) Mus musculus
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Symbol: Dnmt1
Name: DNA methyltransferase (cytosine-5) 1
Description: Exhibits several functions, including DNA (cytosine-5-)-methyltransferase activity; nucleic acid binding activity; and zinc ion binding activity. Involved in several processes, including DNA metabolic process; cellular response to amino acid stimulus; and negative regulation of gene expression. Localizes to the nucleus; pericentric heterochromatin; and replication fork. Human ortholog(s) of this gene implicated in Graves' disease; autosomal dominant cerebellar ataxia, deafness and narcolepsy; hereditary sensory neuropathy; and hereditary sensory neuropathy type 1E. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and integumental system. Orthologous to human DNMT1 (DNA methyltransferase 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Cxxc9; DNA (cytosine-5)-methyltransferase 1; DNA methyltransferase MmuI; DNA MTase MmuI; Dnmt; Dnmt1o; m.MmuI; MCMT; Met-1; Met1; MommeD2; MTase
Orthologs:
Homo sapiens (human) : DNMT1 (DNA methyltransferase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dnmt1 (DNA methyltransferase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dnmt1 (DNA methyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DNMT1 (DNA methyltransferase 1)
Canis lupus familiaris (dog) : DNMT1 (DNA methyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dnmt1 (DNA methyltransferase 1)
Sus scrofa (pig) : DNMT1 (DNA methyltransferase 1)
Chlorocebus sabaeus (green monkey) : DNMT1 (DNA methyltransferase 1)
Heterocephalus glaber (naked mole-rat) : Dnmt1 (DNA methyltransferase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl920,907,209 - 20,959,888 (-)Ensembl
GRCm38920,907,206 - 20,959,888 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37920,711,653 - 20,757,317 (-)NCBIGRCm37mm9NCBIm37
MGSCv36920,657,611 - 20,703,267 (-)NCBImm8
Celera918,175,904 - 18,228,582 (-)NCBICelera
Cytogenetic Map9 A3NCBI
cM Map97.66NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Dnmt1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552151
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-02-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.