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Gene: Galc (galactosylceramidase) Mus musculus
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Symbol: Galc
Name: galactosylceramidase
Description: Exhibits galactosylceramidase activity. Involved in galactosylceramide catabolic process and myelination. Localizes to the mitochondrion. Used to study Krabbe disease. Human ortholog(s) of this gene implicated in Krabbe disease. Is expressed in brain. Orthologous to human GALC (galactosylceramidase).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2310068B06Rik; A930008M05Rik; AW212969; AW413532; Gacy; galactocerebrosidase; galactocerebroside beta-galactosidase; galactosylceramide beta-galactosidase; GALCERase; twi; twitcher
Orthologs:
Homo sapiens (human) : GALC (galactosylceramidase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Galc (galactosylceramidase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Galc (galactosylceramidase)
Pan paniscus (bonobo/pygmy chimpanzee) : GALC (galactosylceramidase)
Canis lupus familiaris (dog) : GALC (galactosylceramidase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Galc (galactosylceramidase)
Sus scrofa (pig) : GALC (galactosylceramidase)
Chlorocebus sabaeus (green monkey) : GALC (galactosylceramidase)
Heterocephalus glaber (naked mole-rat) : Galc (galactosylceramidase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1298,202,294 - 98,259,459 (-)Ensembl
GRCm381298,202,287 - 98,259,459 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371299,440,510 - 99,497,547 (-)NCBIGRCm37mm9NCBIm37
MGSCv361298,603,350 - 98,660,387 (-)NCBImm8
Celera1299,428,771 - 99,485,106 (-)NCBICelera
Cytogenetic Map12 ENCBI
cM Map1249.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Galc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552188
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.