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Gene: Ms4a2 (membrane-spanning 4-domains, subfamily A, member 2) Mus musculus
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Symbol: Ms4a2
Name: membrane-spanning 4-domains, subfamily A, member 2
Description: Contributes to IgE binding activity. Involved in cell surface receptor signaling pathway. Localizes to the Fc-epsilon receptor I complex; external side of plasma membrane; and integral component of plasma membrane. Human ortholog(s) of this gene implicated in asthma; atopic dermatitis; and rhinitis. Is expressed in skin. Orthologous to human MS4A2 (membrane spanning 4-domains A2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: fc epsilon receptor I beta-chain; Fc receptor, IgE, high affinity I, beta polypeptide; Fce1b; Fcer1b; fcERI; FcRB; Fcrbeta; high affinity immunoglobulin epsilon receptor subunit beta; igE Fc receptor subunit beta; membrane-spanning 4-domains subfamily A member 2; membrane-spanning 4-domains, subfamily A, member 1; Ms4a1
Orthologs:
Homo sapiens (human) : MS4A2 (membrane spanning 4-domains A2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ms4a2 (membrane spanning 4-domains A2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ms4a2 (membrane spanning 4-domains A2)
Pan paniscus (bonobo/pygmy chimpanzee) : MS4A2 (membrane spanning 4-domains A2)
Canis lupus familiaris (dog) : MS4A2 (membrane spanning 4-domains A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ms4a2 (membrane spanning 4-domains A2)
Sus scrofa (pig) : MS4A2 (membrane spanning 4-domains A2)
Chlorocebus sabaeus (African green monkey) : MS4A2 (membrane spanning 4-domains A2)
Heterocephalus glaber (naked mole-rat) : Ms4a2 (membrane spanning 4-domains A2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1911,615,523 - 11,623,719 (-)Ensembl
GRCm381911,615,517 - 11,623,790 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371911,691,683 - 11,698,133 (-)NCBIGRCm37mm9NCBIm37
MGSCv361911,684,238 - 11,690,688 (-)NCBImm8
Celera1912,287,403 - 12,295,602 (-)NCBICelera
Cytogenetic Map19 ANCBI
cM Map198.46NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ms4a2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552198
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.