Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ms4a2 (membrane-spanning 4-domains, subfamily A, member 2) Mus musculus
Symbol: Ms4a2
Name: membrane-spanning 4-domains, subfamily A, member 2
Description: Contributes to IgE binding activity. Involved in cell surface receptor signaling pathway. Localizes to the Fc-epsilon receptor I complex; external side of plasma membrane; and integral component of plasma membrane. Human ortholog(s) of this gene implicated in asthma; atopic dermatitis; and rhinitis. Is expressed in skin. Orthologous to human MS4A2 (membrane spanning 4-domains A2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: fc epsilon receptor I beta-chain; Fc receptor, IgE, high affinity I, beta polypeptide; Fce1b; Fcer1b; fcERI; FcRB; Fcrbeta; high affinity immunoglobulin epsilon receptor subunit beta; igE Fc receptor subunit beta; membrane-spanning 4-domains subfamily A member 2; membrane-spanning 4-domains, subfamily A, member 1; Ms4a1
Homo sapiens (human) : MS4A2 (membrane spanning 4-domains A2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ms4a2 (membrane spanning 4-domains A2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ms4a2 (membrane spanning 4-domains A2)
Pan paniscus (bonobo/pygmy chimpanzee) : MS4A2 (membrane spanning 4-domains A2)
Canis lupus familiaris (dog) : MS4A2 (membrane spanning 4-domains A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ms4a2 (membrane spanning 4-domains A2)
Sus scrofa (pig) : MS4A2 (membrane spanning 4-domains A2)
Chlorocebus sabaeus (African green monkey) : MS4A2 (membrane spanning 4-domains A2)
Heterocephalus glaber (naked mole-rat) : Ms4a2 (membrane spanning 4-domains A2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1911,615,523 - 11,623,719 (-)Ensembl
GRCm381911,615,517 - 11,623,790 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371911,691,683 - 11,698,133 (-)NCBIGRCm37mm9NCBIm37
MGSCv361911,684,238 - 11,690,688 (-)NCBImm8
Celera1912,287,403 - 12,295,602 (-)NCBICelera
Cytogenetic Map19 ANCBI
cM Map198.46NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ms4a2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552198
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.