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Gene: Pcsk5 (proprotein convertase subtilisin/kexin type 5) Mus musculus
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Symbol: Pcsk5
Name: proprotein convertase subtilisin/kexin type 5
CRRD ID: 1552230
Description: Exhibits peptide binding activity and serine-type endopeptidase activity. Involved in several processes, including animal organ development; embryo implantation; and peptide metabolic process. Localizes to Golgi apparatus; extracellular space; and secretory granule. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; genitourinary system; and sensory organ. Used to study VACTERL association; primary ciliary dyskinesia; and visceral heterotaxy. Orthologous to human PCSK5 (proprotein convertase subtilisin/kexin type 5).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: b2b1549C; b2b1549Clo; b2b585C; b2b585Clo; PC; PC5; PC5/; PC5/6A; PC5A; PC6; proprotein convertase 5; proprotein convertase 6; proprotein convertase PC5; SP; SPC6; subtilisin-like proprotein convertase 6; subtilisin/kexin-like protease PC5
Orthologs:
Homo sapiens (human) : PCSK5 (proprotein convertase subtilisin/kexin type 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pcsk5 (proprotein convertase subtilisin/kexin type 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pcsk5 (proprotein convertase subtilisin/kexin type 5)
Pan paniscus (bonobo/pygmy chimpanzee) : PCSK5 (proprotein convertase subtilisin/kexin type 5)
Canis lupus familiaris (dog) : PCSK5 (proprotein convertase subtilisin/kexin type 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pcsk5 (proprotein convertase subtilisin/kexin type 5)
Sus scrofa (pig) : PCSK5 (proprotein convertase subtilisin/kexin type 5)
Chlorocebus sabaeus (African green monkey) : PCSK5 (proprotein convertase subtilisin/kexin type 5)
Heterocephalus glaber (naked mole-rat) : Pcsk5 (proprotein convertase subtilisin/kexin type 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1917,432,319 - 17,837,632 (-)EnsemblGRCm38mm10GRCm38
GRCm381917,432,314 - 17,837,712 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371917,507,322 - 17,912,122 (-)NCBIGRCm37mm9NCBIm37
MGSCv361917,499,851 - 17,993,244 (-)NCBImm8
Celera1918,108,836 - 18,517,555 (-)NCBICelera
Cytogenetic Map19BNCBI
cM Map1912.86NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pcsk5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552230
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.