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Gene: Pcsk5 (proprotein convertase subtilisin/kexin type 5) Mus musculus
Symbol: Pcsk5
Name: proprotein convertase subtilisin/kexin type 5
CRRD ID: 1552230
Description: Exhibits peptide binding activity and serine-type endopeptidase activity. Involved in several processes, including animal organ development; embryo implantation; and peptide metabolic process. Localizes to Golgi apparatus; extracellular space; and secretory granule. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; genitourinary system; and sensory organ. Used to study VACTERL association; primary ciliary dyskinesia; and visceral heterotaxy. Orthologous to human PCSK5 (proprotein convertase subtilisin/kexin type 5).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: b2b1549C; b2b1549Clo; b2b585C; b2b585Clo; PC; PC5; PC5/; PC5/6A; PC5A; PC6; proprotein convertase 5; proprotein convertase 6; proprotein convertase PC5; SP; SPC6; subtilisin-like proprotein convertase 6; subtilisin/kexin-like protease PC5
Homo sapiens (human) : PCSK5 (proprotein convertase subtilisin/kexin type 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pcsk5 (proprotein convertase subtilisin/kexin type 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pcsk5 (proprotein convertase subtilisin/kexin type 5)
Pan paniscus (bonobo/pygmy chimpanzee) : PCSK5 (proprotein convertase subtilisin/kexin type 5)
Canis lupus familiaris (dog) : PCSK5 (proprotein convertase subtilisin/kexin type 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pcsk5 (proprotein convertase subtilisin/kexin type 5)
Sus scrofa (pig) : PCSK5 (proprotein convertase subtilisin/kexin type 5)
Chlorocebus sabaeus (African green monkey) : PCSK5 (proprotein convertase subtilisin/kexin type 5)
Heterocephalus glaber (naked mole-rat) : Pcsk5 (proprotein convertase subtilisin/kexin type 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1917,432,319 - 17,837,632 (-)EnsemblGRCm38mm10GRCm38
GRCm381917,432,314 - 17,837,712 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371917,507,322 - 17,912,122 (-)NCBIGRCm37mm9NCBIm37
MGSCv361917,499,851 - 17,993,244 (-)NCBImm8
Celera1918,108,836 - 18,517,555 (-)NCBICelera
Cytogenetic Map19BNCBI
cM Map1912.86NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pcsk5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552230
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.