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Gene: Axin1 (axin 1) Mus musculus
Symbol: Axin1
Name: axin 1
CRRD ID: 1552250
Description: Exhibits several functions, including SMAD binding activity; beta-catenin binding activity; and enzyme binding activity. Involved in several processes, including chordate embryonic development; positive regulation of cellular protein metabolic process; and regulation of transcription, DNA-templated. Localizes to several cellular components, including Wnt signalosome; beta-catenin destruction complex; and cell cortex. Colocalizes with cytoplasmic microtubule. Is expressed in several structures, including forebrain; jaw; lung; retina; and urinary system. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human AXIN1 (axin 1); PARTICIPATES IN altered Wnt signaling, canonical pathway; colorectal cancer pathway; N-cadherin signaling pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,2-dimethylhydrazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI316800; Axin; axin-1; axis inhibition protein 1; Fu; fused; Kb; Ki; kinky; knobbly; MGC132911
Homo sapiens (human) : AXIN1 (axin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Axin1 (axin 1)
Chinchilla lanigera (long-tailed chinchilla) : Axin1 (axin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AXIN1 (axin 1)
Canis lupus familiaris (dog) : AXIN1 (axin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Axin1 (axin 1)
Sus scrofa (pig) : AXIN1 (axin 1)
Chlorocebus sabaeus (African green monkey) : AXIN1 (axin 1)
Heterocephalus glaber (naked mole-rat) : Axin1 (axin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391726,350,208 - 26,414,785 (+)NCBI
GRCm381726,131,217 - 26,195,811 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1726,138,688 - 26,195,811 (+)EnsemblGRCm38mm10GRCm38
MGSCv371726,275,631 - 26,332,756 (+)NCBIGRCm37mm9NCBIm37
MGSCv361725,866,334 - 25,923,411 (+)NCBImm8
Celera1726,676,271 - 26,729,569 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1713.07NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Axin1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552250
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.