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Gene: Btrc (beta-transducin repeat containing protein) Mus musculus
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Symbol: Btrc
Name: beta-transducin repeat containing protein
Description: Exhibits beta-catenin binding activity; protein phosphorylated amino acid binding activity; and ubiquitin protein ligase activity. Predicted to contribute to ubiquitin-protein transferase activity. Involved in several processes, including cellular protein metabolic process; mammary gland epithelium development; and regulation of signal transduction. Localizes to cytoplasm and nucleus. Is expressed in central nervous system; dorsal root ganglion; genitourinary system; and liver. Orthologous to human BTRC (beta-transducin repeat containing E3 ubiquitin protein ligase); PARTICIPATES IN Hedgehog signaling pathway; nuclear factor kappa B signaling pathway; nuclear factor, erythroid 2 like 2 signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 5-aza-2'-deoxycytidine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: b-TrCP; beta-transducin repeat-containing protein; beta-TrCP; beta-TrCP protein E3RS-IkappaB; Beta-Trcp1; E3RS-IkappaB; E3RSIkappaB; F-box and WD repeats protein beta-TrCP; F-box/WD repeat-containing protein 1A; Fbw1a; FWD1; HOS; KIAA4123; mE3RS-IkappaB; mKIAA4123; pIkappaB-E3 receptor subunit; SCF b-TRCP; Slimb; ubiquitin ligase FWD1
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1945,363,734 - 45,530,013 (+)EnsemblGRCm38mm10GRCm38
GRCm381945,363,688 - 45,533,343 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371945,438,224 - 45,607,833 (+)NCBIGRCm37mm9NCBIm37
MGSCv361945,409,208 - 45,583,324 (+)NCBImm8
Celera1946,131,196 - 46,300,930 (+)NCBICelera
Cytogenetic Map19C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Btrc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552424
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.