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Gene: Herc1 (HECT and RLD domain containing E3 ubiquitin protein ligase family member 1) Mus musculus
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Symbol: Herc1
Name: HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Description: Involved in negative regulation of autophagy; neuromuscular process controlling balance; and neuron differentiation. Is expressed in several structures, including jaw bone; nervous system; sensory organ; thymus primordium; and vibrissa. Orthologous to human HERC1 (HECT and RLD domain containing E3 ubiquitin protein ligase family member 1); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 3,4-methylenedioxymethamphetamine; aflatoxin B1; clobetasol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2810449H11Rik; B230218H07; D130015N03Rik; hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1; hect domain and RCC1-like domain 1; MGC7618; probable E3 ubiquitin-protein ligase HERC1; tbl
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38966,350,412 - 66,508,775 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37966,198,257 - 66,356,582 (+)NCBIGRCm37mm9NCBIm37
MGSCv36966,148,456 - 66,309,055 (+)NCBImm8
Celera963,584,587 - 63,742,741 (+)NCBICelera
Cytogenetic Map9 CNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Herc1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552425
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.