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Gene: Pabpc1 (poly(A) binding protein, cytoplasmic 1) Mus musculus
Symbol: Pabpc1
Name: poly(A) binding protein, cytoplasmic 1
Description: Predicted to have RNA binding activity and protein C-terminus binding activity. Involved in gene silencing by RNA and positive regulation of nuclear-transcribed mRNA poly(A) tail shortening. Localizes to the cytoplasm and synapse. Is expressed in several structures, including central nervous system; gonad; gut; sensory organ; and spleen. Orthologous to several human genes including PABPC1 (poly(A) binding protein cytoplasmic 1); PARTICIPATES IN microRNA pathway; translation initiation pathway; mRNA decay pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ePAB; PABP; PABP-1; Pabp1; PabpI; Pabpl1; poly A binding protein 1; poly(A)-binding protein 1; polyadenylate-binding protein 1
Homo sapiens (human) : PABPC1 (poly(A) binding protein cytoplasmic 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pabpc1 (poly(A) binding protein, cytoplasmic 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pabpc1 (poly(A) binding protein cytoplasmic 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PABPC1 (poly(A) binding protein cytoplasmic 1)
Canis lupus familiaris (dog) : PABPC1 (poly(A) binding protein cytoplasmic 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pabpc1 (poly(A) binding protein cytoplasmic 1)
Sus scrofa (pig) : PABPC1 (poly(A) binding protein cytoplasmic 1)
Chlorocebus sabaeus (African green monkey) : PABPC1 (poly(A) binding protein cytoplasmic 1)
Heterocephalus glaber (naked mole-rat) : Pabpc1 (poly(A) binding protein cytoplasmic 1)
more info ...
Related Pseudogenes: Gm16580   Gm18790   Gm18793   Gm8276   Pabpc1l2a-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1536,595,661 - 36,609,668 (-)EnsemblGRCm38mm10GRCm38
GRCm381536,595,658 - 36,609,581 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371536,525,413 - 36,538,728 (-)NCBIGRCm37mm9NCBIm37
MGSCv361536,540,252 - 36,553,551 (-)NCBImm8
Celera1537,216,852 - 37,230,173 (-)NCBICelera
Cytogenetic Map15B3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pabpc1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552448
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.