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Gene: Pabpc1 (poly(A) binding protein, cytoplasmic 1) Mus musculus
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Symbol: Pabpc1
Name: poly(A) binding protein, cytoplasmic 1
Description: Predicted to have RNA binding activity and protein C-terminus binding activity. Involved in gene silencing by RNA and positive regulation of nuclear-transcribed mRNA poly(A) tail shortening. Localizes to the cytoplasm and synapse. Is expressed in several structures, including central nervous system; gonad; gut; sensory organ; and spleen. Orthologous to several human genes including PABPC1 (poly(A) binding protein cytoplasmic 1); PARTICIPATES IN microRNA pathway; translation initiation pathway; mRNA decay pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ePAB; PABP; PABP-1; Pabp1; PabpI; Pabpl1; poly A binding protein 1; poly(A)-binding protein 1; polyadenylate-binding protein 1
Orthologs:
Homo sapiens (human) : PABPC1 (poly(A) binding protein cytoplasmic 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pabpc1 (poly(A) binding protein, cytoplasmic 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pabpc1 (poly(A) binding protein cytoplasmic 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PABPC1 (poly(A) binding protein cytoplasmic 1)
Canis lupus familiaris (dog) : PABPC1 (poly(A) binding protein cytoplasmic 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pabpc1 (poly(A) binding protein cytoplasmic 1)
Sus scrofa (pig) : PABPC1 (poly(A) binding protein cytoplasmic 1)
Chlorocebus sabaeus (African green monkey) : PABPC1 (poly(A) binding protein cytoplasmic 1)
Heterocephalus glaber (naked mole-rat) : Pabpc1 (poly(A) binding protein cytoplasmic 1)
more info ...
Related Pseudogenes: Gm16580   Gm18790   Gm18793   Gm8276   Pabpc1l2a-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1536,595,661 - 36,609,668 (-)EnsemblGRCm38mm10GRCm38
GRCm381536,595,658 - 36,609,581 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371536,525,413 - 36,538,728 (-)NCBIGRCm37mm9NCBIm37
MGSCv361536,540,252 - 36,553,551 (-)NCBImm8
Celera1537,216,852 - 37,230,173 (-)NCBICelera
Cytogenetic Map15B3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pabpc1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552448
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.