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Gene: Bak1 (BCL2-antagonist/killer 1) Mus musculus
Symbol: Bak1
Name: BCL2-antagonist/killer 1
Description: Exhibits identical protein binding activity. Involved in several processes, including apoptotic signaling pathway; cellular calcium ion homeostasis; and lymphocyte apoptotic process. Localizes to several cellular components, including the BAK complex; endoplasmic reticulum; and integral component of mitochondrial outer membrane. Human ortholog(s) of this gene implicated in ataxia telangiectasia and cervix carcinoma. Is expressed in several structures, including alimentary system; brain; branchial arch; genitourinary system; and hemolymphoid system gland. Orthologous to human BAK1 (BCL2 antagonist/killer 1); PARTICIPATES IN intrinsic apoptotic pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (+)-dexrazoxane; 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: apoptosis regulator BAK; Bak; bcl-2 homologous antagonist/killer; Bcl2 homologous antagonist/killer; N-Bak; N-BAK1
Homo sapiens (human) : BAK1 (BCL2 antagonist/killer 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Bak1 (BCL2-antagonist/killer 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bak1 (BCL2 antagonist/killer 1)
Pan paniscus (bonobo/pygmy chimpanzee) : BAK1 (BCL2 antagonist/killer 1)
Canis lupus familiaris (dog) : BAK1 (BCL2 antagonist/killer 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bak1 (BCL2 antagonist/killer 1)
Sus scrofa (pig) : BAK1 (BCL2 antagonist/killer 1)
Chlorocebus sabaeus (African green monkey) : BAK1 (BCL2 antagonist/killer 1)
Heterocephalus glaber (naked mole-rat) : Bak1 (BCL2 antagonist/killer 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1727,019,810 - 27,029,009 (-)Ensembl
GRCm381727,019,812 - 27,028,627 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371727,156,757 - 27,165,571 (-)NCBIGRCm37mm9NCBIm37
MGSCv361726,747,401 - 26,756,216 (-)NCBImm8
Celera1727,556,267 - 27,565,056 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Bak1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552456
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-02-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.