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Gene: Bak1 (BCL2-antagonist/killer 1) Mus musculus
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Symbol: Bak1
Name: BCL2-antagonist/killer 1
Description: Exhibits identical protein binding activity. Involved in several processes, including apoptotic signaling pathway; cellular calcium ion homeostasis; and lymphocyte apoptotic process. Localizes to several cellular components, including the BAK complex; endoplasmic reticulum; and integral component of mitochondrial outer membrane. Human ortholog(s) of this gene implicated in ataxia telangiectasia and cervix carcinoma. Is expressed in several structures, including alimentary system; brain; branchial arch; genitourinary system; and hemolymphoid system gland. Orthologous to human BAK1 (BCL2 antagonist/killer 1); PARTICIPATES IN intrinsic apoptotic pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (+)-dexrazoxane; 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: apoptosis regulator BAK; Bak; bcl-2 homologous antagonist/killer; Bcl2 homologous antagonist/killer; N-Bak; N-BAK1
Orthologs:
Homo sapiens (human) : BAK1 (BCL2 antagonist/killer 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Bak1 (BCL2-antagonist/killer 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bak1 (BCL2 antagonist/killer 1)
Pan paniscus (bonobo/pygmy chimpanzee) : BAK1 (BCL2 antagonist/killer 1)
Canis lupus familiaris (dog) : BAK1 (BCL2 antagonist/killer 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bak1 (BCL2 antagonist/killer 1)
Sus scrofa (pig) : BAK1 (BCL2 antagonist/killer 1)
Chlorocebus sabaeus (African green monkey) : BAK1 (BCL2 antagonist/killer 1)
Heterocephalus glaber (naked mole-rat) : Bak1 (BCL2 antagonist/killer 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1727,019,810 - 27,029,009 (-)Ensembl
GRCm381727,019,812 - 27,028,627 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371727,156,757 - 27,165,571 (-)NCBIGRCm37mm9NCBIm37
MGSCv361726,747,401 - 26,756,216 (-)NCBImm8
Celera1727,556,267 - 27,565,056 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Bak1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552456
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-02-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.