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Gene: Rnf146 (ring finger protein 146) Mus musculus
Symbol: Rnf146
Name: ring finger protein 146
Description: Predicted to have poly-ADP-D-ribose binding activity and ubiquitin-protein transferase activity. Predicted to be involved in several processes, including negative regulation of hydrogen peroxide-induced cell death; positive regulation of canonical Wnt signaling pathway; and protein ubiquitination. Predicted to localize to the cytosol; nucleoplasm; and plasma membrane. Used to study cleidocranial dysplasia. Is expressed in genitourinary system. Orthologous to human RNF146 (ring finger protein 146); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610509H23Rik; E3 ubiquitin-protein ligase RNF146; Iduna; RING-type E3 ubiquitin transferase RNF146
Homo sapiens (human) : RNF146 (ring finger protein 146)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rnf146 (ring finger protein 146)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rnf146 (ring finger protein 146)
Pan paniscus (bonobo/pygmy chimpanzee) : RNF146 (ring finger protein 146)
Canis lupus familiaris (dog) : RNF146 (ring finger protein 146)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rnf146 (ring finger protein 146)
Sus scrofa (pig) : RNF146 (ring finger protein 146)
Chlorocebus sabaeus (green monkey) : RNF146 (ring finger protein 146)
Heterocephalus glaber (naked mole-rat) : Rnf146 (ring finger protein 146)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1029,344,176 - 29,362,442 (-)Ensembl
GRCm381029,344,176 - 29,362,442 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371029,063,982 - 29,082,248 (-)NCBIGRCm37mm9NCBIm37
MGSCv361029,035,587 - 29,051,858 (-)NCBImm8
Celera1030,276,585 - 30,294,697 (-)NCBICelera
Cytogenetic Map10 A4NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Rnf146
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552458
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-12-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.