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Gene: Slc39a4 (solute carrier family 39 (zinc transporter), member 4) Mus musculus
Symbol: Slc39a4
Name: solute carrier family 39 (zinc transporter), member 4
Description: Exhibits zinc ion transmembrane transporter activity. Involved in cellular response to zinc ion starvation; cellular zinc ion homeostasis; and zinc ion transport. Localizes to the apical plasma membrane and endosome. Used to study acrodermatitis enteropathica. Human ortholog(s) of this gene implicated in acrodermatitis enteropathica. Is expressed in several structures, including alimentary system; early embryo; extraembryonic component; integumental system; and liver. Orthologous to human SLC39A4 (solute carrier family 39 member 4); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1600025H15Rik; activated in W/Wv mouse stomach 2; AU041686; AWMS2; mAWMS2; solute carrier family 39 member 4; zinc transporter ZIP4; ZIP-4; ZIP4; zrt- and Irt-like protein 4
Homo sapiens (human) : SLC39A4 (solute carrier family 39 member 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Slc39a4 (solute carrier family 39 member 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc39a4 (solute carrier family 39 member 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC39A4 (solute carrier family 39 member 4)
Canis lupus familiaris (dog) : SLC39A4 (solute carrier family 39 member 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc39a4 (solute carrier family 39 member 4)
Sus scrofa (pig) : SLC39A4 (solute carrier family 39 member 4)
Chlorocebus sabaeus (African green monkey) : SLC39A4 (solute carrier family 39 member 4)
Heterocephalus glaber (naked mole-rat) : Slc39a4 (solute carrier family 39 member 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1576,612,383 - 76,617,384 (-)EnsemblGRCm38mm10GRCm38
GRCm381576,612,383 - 76,618,506 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371576,442,813 - 76,447,282 (-)NCBIGRCm37mm9NCBIm37
MGSCv361576,439,638 - 76,444,107 (-)NCBImm8
Celera1578,105,998 - 78,110,467 (-)NCBICelera
Cytogenetic Map15D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Slc39a4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552511
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.