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Gene: Lzts2 (leucine zipper, putative tumor suppressor 2) Mus musculus
Symbol: Lzts2
Name: leucine zipper, putative tumor suppressor 2
Description: Involved in several processes, including negative regulation of canonical Wnt signaling pathway; negative regulation of protein localization to nucleus; and renal system development. Localizes to cytoplasm. Is expressed in several structures, including 1st branchial arch mandibular component; adrenal gland; future brain; genitourinary system; and limb. Used to study urinary system disease. Orthologous to human LZTS2 (leucine zipper tumor suppressor 2); INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BC014695; LAPSER1; leucine zipper putative tumor suppressor 2; MGC7094; mKIAA1813; putative tumor suppressor LAPSER1
Homo sapiens (human) : LZTS2 (leucine zipper tumor suppressor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lzts2 (leucine zipper tumor suppressor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lzts2 (leucine zipper tumor suppressor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : LZTS2 (leucine zipper tumor suppressor 2)
Canis lupus familiaris (dog) : LZTS2 (leucine zipper tumor suppressor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lzts2 (leucine zipper tumor suppressor 2)
Sus scrofa (pig) : LZTS2 (leucine zipper tumor suppressor 2)
Chlorocebus sabaeus (African green monkey) : LZTS2 (leucine zipper tumor suppressor 2)
Heterocephalus glaber (naked mole-rat) : Lzts2 (leucine zipper tumor suppressor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1945,014,414 - 45,027,111 (+)EnsemblGRCm38mm10GRCm38
GRCm381945,015,176 - 45,027,115 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371945,089,666 - 45,101,594 (+)NCBIGRCm37mm9NCBIm37
MGSCv361945,074,701 - 45,080,400 (+)NCBImm8
Celera1945,785,852 - 45,797,580 (+)NCBICelera
Cytogenetic Map19C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Lzts2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552566
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-06-19
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.