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Gene: Lmx1b (LIM homeobox transcription factor 1 beta) Mus musculus
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Symbol: Lmx1b
Name: LIM homeobox transcription factor 1 beta
Description: Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in several processes, including collagen fibril organization; nervous system development; and trabecular meshwork development. Localizes to the nucleus. Used to study nail-patella syndrome. Human ortholog(s) of this gene implicated in nail-patella syndrome. Is expressed in several structures, including central nervous system; hemolymphoid system; limb; respiratory system; and trunk mesenchyme. Orthologous to human LMX1B (LIM homeobox transcription factor 1 beta); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GENA 191; Icst; LIM homeo box transcription factor 1B; LIM homeobox transcription factor 1-beta; LIM/homeobox protein 1.2; LIM/homeobox protein LMX1B; LMX-1.2; LMX1.1; LMX1.2; MGC159172
Orthologs:
Homo sapiens (human) : LMX1B (LIM homeobox transcription factor 1 beta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lmx1b (LIM homeobox transcription factor 1 beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lmx1b (LIM homeobox transcription factor 1 beta)
Pan paniscus (bonobo/pygmy chimpanzee) : LMX1B (LIM homeobox transcription factor 1 beta)
Canis lupus familiaris (dog) : LMX1B (LIM homeobox transcription factor 1 beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lmx1b (LIM homeobox transcription factor 1 beta)
Sus scrofa (pig) : LMX1B (LIM homeobox transcription factor 1 beta)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38233,560,965 - 33,641,208 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37233,420,056 - 33,496,031 (-)NCBIGRCm37mm9NCBIm37
MGSCv36233,386,645 - 33,462,520 (-)NCBImm8
Celera233,269,132 - 33,345,093 (-)NCBICelera
Cytogenetic Map2 BNCBI
cM Map222.48NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on Lmx1b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552590
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.