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Gene: Lmx1b (LIM homeobox transcription factor 1 beta) Mus musculus
Symbol: Lmx1b
Name: LIM homeobox transcription factor 1 beta
Description: Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in several processes, including collagen fibril organization; nervous system development; and trabecular meshwork development. Localizes to the nucleus. Used to study nail-patella syndrome. Human ortholog(s) of this gene implicated in nail-patella syndrome. Is expressed in several structures, including central nervous system; hemolymphoid system; limb; respiratory system; and trunk mesenchyme. Orthologous to human LMX1B (LIM homeobox transcription factor 1 beta); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GENA 191; Icst; LIM homeo box transcription factor 1B; LIM homeobox transcription factor 1-beta; LIM/homeobox protein 1.2; LIM/homeobox protein LMX1B; LMX-1.2; LMX1.1; LMX1.2; MGC159172
Homo sapiens (human) : LMX1B (LIM homeobox transcription factor 1 beta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lmx1b (LIM homeobox transcription factor 1 beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lmx1b (LIM homeobox transcription factor 1 beta)
Pan paniscus (bonobo/pygmy chimpanzee) : LMX1B (LIM homeobox transcription factor 1 beta)
Canis lupus familiaris (dog) : LMX1B (LIM homeobox transcription factor 1 beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lmx1b (LIM homeobox transcription factor 1 beta)
Sus scrofa (pig) : LMX1B (LIM homeobox transcription factor 1 beta)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38233,560,965 - 33,641,208 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37233,420,056 - 33,496,031 (-)NCBIGRCm37mm9NCBIm37
MGSCv36233,386,645 - 33,462,520 (-)NCBImm8
Celera233,269,132 - 33,345,093 (-)NCBICelera
Cytogenetic Map2 BNCBI
cM Map222.48NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Lmx1b
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552590
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.