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Gene: Hsp90ab1 (heat shock protein 90 alpha (cytosolic), class B member 1) Mus musculus
Symbol: Hsp90ab1
Name: heat shock protein 90 alpha (cytosolic), class B member 1
CRRD ID: 1552591
Description: Exhibits protein folding chaperone; protein kinase binding activity; and tau protein binding activity. Contributes to protein kinase regulator activity. Involved in several processes, including axonogenesis; positive regulation of protein kinase B signaling; and regulation of cellular protein metabolic process. Localizes to several cellular components, including HSP90-CDC37 chaperone complex; growth cone; and neuronal cell body. Predicted to colocalize with COP9 signalosome. Is expressed in several structures, including branchial arch; central nervous system; eye; future brain; and placenta. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human HSP90AB1 (heat shock protein 90 alpha family class B member 1); PARTICIPATES IN aldosterone signaling pathway; androgen signaling pathway; cortisol signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-hydroxy-5alpha-androstan-3-one.
Type: protein-coding
Also known as: 90kDa; AL022974; C81438; heat shock 84 kDa; heat shock 90kDa protein 1, beta; heat shock protein 1, beta; heat shock protein 90kDa alpha (cytosolic), class B member 1; heat shock protein HSP 90-beta; heat shock protein, 84 kDa 1; Hsp; HSP 84; Hsp84; Hsp84-1; Hsp90; Hspcb; MGC115780; retinal degeneration slow protein; TSTA; tumor-specific transplantation 84 kDa antigen
Related Pseudogenes: Gm11875   Gm11983   Gm12010   Gm13498   Gm14606   Gm14910   Gm14917   Gm15170   Gm15189   Gm19122   Gm19123   Gm19124   Gm19125   Gm19131   Gm19134   Gm19135   Gm19137   Gm19139   Gm19141   Gm19829   Gm2970   Gm5715   Gm6368   Gm7002   Gm7198   Gm7425   Gm9403   Gm9408  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391745,878,704 - 45,884,187 (-)NCBI
GRCm381745,567,778 - 45,573,261 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1745,567,775 - 45,573,271 (-)EnsemblGRCm38mm10GRCm38
MGSCv371745,704,727 - 45,710,210 (-)NCBIGRCm37mm9NCBIm37
MGSCv361745,031,359 - 45,036,842 (-)NCBImm8
Celera1749,000,428 - 49,005,921 (-)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1722.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hsp90ab1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552591
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-11-03
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.