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Gene: Prkaca (protein kinase, cAMP dependent, catalytic, alpha) Mus musculus
Symbol: Prkaca
Name: protein kinase, cAMP dependent, catalytic, alpha
CRRD ID: 1552640
Description: Exhibits several functions, including ATP binding activity; cAMP-dependent protein kinase activity; and metal ion binding activity. Involved in several processes, including cellular response to parathyroid hormone stimulus; embryonic morphogenesis; and protein phosphorylation. Localizes to several cellular components, including acrosomal vesicle; cAMP-dependent protein kinase complex; and ciliary base. Predicted to colocalize with axoneme. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and musculature. Human ortholog(s) of this gene implicated in adrenal cortical adenoma; congestive heart failure; hypertrophic cardiomyopathy; and primary pigmented nodular adrenocortical disease. Orthologous to human PRKACA (protein kinase cAMP-activated catalytic subunit alpha).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C; cAMP-dependent protein kinase catalytic subunit alpha; cAMP-dependent protein kinase catalytic subunit alpha isoform; cAMP-dependent protein kinase catalytic subunit C alpha 2; Cs; P; Pk; PKA; PKA C-alpha; Pkaca; PKCD; sperm cAMP-dependent protein kinase catalytic subunit
Related Pseudogenes: Prkaca-ps1  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl883,972,993 - 83,996,443 (+)EnsemblGRCm38mm10GRCm38
GRCm38883,972,978 - 83,996,444 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37886,496,877 - 86,520,344 (+)NCBIGRCm37mm9NCBIm37
MGSCv36886,863,093 - 86,886,544 (+)NCBImm8
Celera888,266,474 - 88,289,645 (+)NCBICelera
Cytogenetic Map8C2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Prkaca
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552640
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.