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Gene: Elac2 (elaC ribonuclease Z 2) Mus musculus
Symbol: Elac2
Name: elaC ribonuclease Z 2
Description: Predicted to have tRNA-specific ribonuclease activity. Predicted to be involved in mitochondrial tRNA 3'-trailer cleavage, endonucleolytic. Localizes to mitochondrial nucleoid. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 17. Is expressed in extraembryonic component. Orthologous to human ELAC2 (elaC ribonuclease Z 2); PARTICIPATES IN tRNA maturation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110017O07Rik; D11Wsu80e; elaC homolog 2; elaC homolog protein 2; Hpc2; ribonuclease Z 2; RNase Z 2; tRNA 3 endonuclease 2; tRNase Z 2; tRNase Z(L); zinc phosphodiesterase ELAC protein 2
Homo sapiens (human) : ELAC2 (elaC ribonuclease Z 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Elac2 (elaC ribonuclease Z 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Elac2 (elaC ribonuclease Z 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ELAC2 (elaC ribonuclease Z 2)
Canis lupus familiaris (dog) : ELAC2 (elaC ribonuclease Z 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Elac2 (elaC ribonuclease Z 2)
Sus scrofa (pig) : ELAC2 (elaC ribonuclease Z 2)
Chlorocebus sabaeus (African green monkey) : ELAC2 (elaC ribonuclease Z 2)
Heterocephalus glaber (naked mole-rat) : Elac2 (elaC ribonuclease Z 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1164,979,038 - 65,002,069 (+)EnsemblGRCm38mm10GRCm38
GRCm381164,979,030 - 65,002,080 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371164,792,537 - 64,815,578 (+)NCBIGRCm37mm9NCBIm37
MGSCv361164,795,292 - 64,818,264 (+)NCBImm8
Celera1171,914,934 - 71,938,052 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1140.42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Elac2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552652
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.