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Gene: Ubr5 (ubiquitin protein ligase E3 component n-recognin 5) Mus musculus
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Symbol: Ubr5
Name: ubiquitin protein ligase E3 component n-recognin 5
CRRD ID: 1552737
Description: Predicted to have ubiquitin-ubiquitin ligase activity. Involved in negative regulation of interleukin-17 production and regulation of protein stability. Predicted to localize to several cellular components, including cytosol; nucleoplasm; and perinuclear region of cytoplasm. Is expressed in cranial ganglion; nervous system; sensory organ; submandibular gland primordium; and vibrissa. Human ortholog(s) of this gene implicated in invasive ductal carcinoma. Orthologous to human UBR5 (ubiquitin protein ligase E3 component n-recognin 5); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4432411E13Rik; AW549941; C77315; D030042K14; E3 ubiquitin protein ligase, HECT domain containing, 1; E3 ubiquitin-protein ligase UBR5; E3 ubiquitin-protein ligase, HECT domain-containing 1; Edd; Edd1; extraembryonic development; HECT-type E3 ubiquitin transferase UBR5; hyperplastic discs protein homolog; mKIAA0896
Orthologs:
Related Pseudogenes: Gm19037  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391537,966,421 - 38,084,103 (-)NCBI
GRCm381537,967,328 - 38,078,862 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1537,967,328 - 38,078,854 (-)EnsemblGRCm38mm10GRCm38
MGSCv371537,897,083 - 38,008,608 (-)NCBIGRCm37mm9NCBIm37
MGSCv361537,911,917 - 38,023,442 (-)NCBImm8
Celera1538,586,135 - 38,667,882 (-)NCBICelera
Cytogenetic Map15B3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ubr5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552737
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.