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Gene: Serping1 (serine (or cysteine) peptidase inhibitor, clade G, member 1) Mus musculus
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Symbol: Serping1
Name: serine (or cysteine) peptidase inhibitor, clade G, member 1
Description: Exhibits complement binding activity and serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of complement activation, lectin pathway and negative regulation of endopeptidase activity. Localizes to the extracellular space. Human ortholog(s) of this gene implicated in angioedema (multiple); cerebral infarction; macular degeneration; pancreatitis; and toxic shock syndrome. Is expressed in genitourinary system; neural ectoderm; notochord; and pancreas mesenchyme. Orthologous to human SERPING1 (serpin family G member 1); PARTICIPATES IN coagulation cascade pathway; kallikrein-kinin cascade pathway; complement system pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C1 esterase inhibitor; C1 Inh; C1 inhibitor; C1-inhibiting factor; C1INH; C1nh; complement component 1 inhibitor; plasma protease C1 inhibitor; serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1; serine (or cysteine) proteinase inhibitor, clade G, member 1; serpin G1
Orthologs:
Homo sapiens (human) : SERPING1 (serpin family G member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Serping1 (serpin family G member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serping1 (serpin family G member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPING1 (serpin family G member 1)
Canis lupus familiaris (dog) : SERPING1 (serpin family G member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serping1 (serpin family G member 1)
Sus scrofa (pig) : SERPING1 (serpin family G member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl284,765,387 - 84,775,444 (-)Ensembl
GRCm38284,765,360 - 84,775,444 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37284,605,517 - 84,615,586 (-)NCBIGRCm37mm9NCBIm37
MGSCv36284,566,224 - 84,576,243 (-)NCBImm8
Celera286,360,569 - 86,370,824 (-)NCBICelera
Cytogenetic Map2 DNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Serping1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552805
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.