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Gene: Nlrp6 (NLR family, pyrin domain containing 6) Mus musculus
Symbol: Nlrp6
Name: NLR family, pyrin domain containing 6
Description: Predicted to have peptide binding activity and vasopressin receptor activity. Involved in several processes, including negative regulation of inflammatory response to antigenic stimulus; negative regulation of signal transduction; and regulation of mucus secretion. Predicted to localize to inflammasome complex; nucleus; and plasma membrane. Is expressed in thymus primordium. Orthologous to human NLRP6 (NLR family pyrin domain containing 6).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI504961; angiotensin II/vasopressin receptor; Avr; NACHT, leucine rich repeat and PYD containing 6; NACHT, LRR and PYD domains-containing protein 6; NACHT/LRR/pyrin domain-containing protein 6; Nalp6; Navr; Navr/Avr; non-angiotensin-vasopressin receptor; Non-AVR; Pypaf5; PYRIN-containing APAF1-like protein 5; PYRIN-containing APAF1-like protein 5-like
Homo sapiens (human) : NLRP6 (NLR family pyrin domain containing 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nlrp6 (NLR family, pyrin domain containing 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nlrp6 (NLR family pyrin domain containing 6)
Pan paniscus (bonobo/pygmy chimpanzee) : NLRP6 (NLR family pyrin domain containing 6)
Canis lupus familiaris (dog) : NLRP6 (NLR family pyrin domain containing 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nlrp6 (NLR family pyrin domain containing 6)
Sus scrofa (pig) : NLRP6 (NLR family pyrin domain containing 6)
Chlorocebus sabaeus (African green monkey) : NLRP6 (NLR family pyrin domain containing 6)
Heterocephalus glaber (naked mole-rat) : Nlrp6 (NLR family pyrin domain containing 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl7140,920,902 - 140,929,192 (+)EnsemblGRCm38mm10GRCm38
GRCm387140,920,902 - 140,929,192 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377148,106,801 - 148,114,439 (+)NCBIGRCm37mm9NCBIm37
MGSCv367140,772,222 - 140,779,860 (+)NCBImm8
Celera7140,713,222 - 140,720,860 (+)NCBICelera
Cytogenetic Map7F5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Nlrp6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552887
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.