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Gene: Pbx1 (pre B cell leukemia homeobox 1) Mus musculus
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Symbol: Pbx1
Name: pre B cell leukemia homeobox 1
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to contribute to RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; positive regulation of G2/M transition of mitotic cell cycle; and regionalization. Localizes to cytoplasm; nucleus; and transcription factor complex. Is expressed in several structures, including alimentary system; brain; branchial arch; embryo mesenchyme; and genitourinary system. Orthologous to human PBX1 (PBX homeobox 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2310056B04Rik; AI848790; AU015730; D230003C07Rik; homeobox protein PBX1; Pbx-1; Pbx1a; Pbx1b; pre B-cell leukemia transcription factor 1; pre-B-cell leukemia transcription factor 1
Orthologs:
Homo sapiens (human) : PBX1 (PBX homeobox 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pbx1 (PBX homeobox 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pbx1 (PBX homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PBX1 (PBX homeobox 1)
Canis lupus familiaris (dog) : PBX1 (PBX homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pbx1 (PBX homeobox 1)
Sus scrofa (pig) : PBX1 (PBX homeobox 1)
Chlorocebus sabaeus (African green monkey) : PBX1 (PBX homeobox 1)
Heterocephalus glaber (naked mole-rat) : Pbx1 (PBX homeobox 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1168,119,364 - 168,432,270 (-)EnsemblGRCm38mm10GRCm38
GRCm381168,119,364 - 168,432,365 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371170,049,495 - 170,362,389 (-)NCBIGRCm37mm9NCBIm37
MGSCv361169,328,392 - 169,641,347 (-)NCBImm8
MGSCv361169,956,674 - 170,268,631 (-)NCBImm8
Celera1170,542,293 - 170,864,365 (-)NCBICelera
Cytogenetic Map1H2.3NCBI
cM Map175.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Pbx1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552910
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.