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Gene: Sgpp1 (sphingosine-1-phosphate phosphatase 1) Mus musculus
Symbol: Sgpp1
Name: sphingosine-1-phosphate phosphatase 1
Description: Exhibits sphingosine-1-phosphate phosphatase activity. Involved in apoptotic signaling pathway; regulation of keratinocyte differentiation; and sphingolipid metabolic process. Localizes to the endoplasmic reticulum and membrane. Is expressed in several structures, including adrenal gland; alimentary system; heart; liver; and urinary system. Orthologous to human SGPP1 (sphingosine-1-phosphate phosphatase 1); PARTICIPATES IN sphingosine 1-phosphate signaling pathway; sphingolipid metabolic pathway; INTERACTS WITH (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI463453; sphingosine-1-phosphatase 1; SPP; SPP1; SPPase1; Spph1
Homo sapiens (human) : SGPP1 (sphingosine-1-phosphate phosphatase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sgpp1 (sphingosine-1-phosphate phosphatase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sgpp1 (sphingosine-1-phosphate phosphatase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SGPP1 (sphingosine-1-phosphate phosphatase 1)
Canis lupus familiaris (dog) : SGPP1 (sphingosine-1-phosphate phosphatase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sgpp1 (sphingosine-1-phosphate phosphatase 1)
Sus scrofa (pig) : SGPP1 (sphingosine-1-phosphate phosphatase 1)
Chlorocebus sabaeus (African green monkey) : SGPP1 (sphingosine-1-phosphate phosphatase 1)
Heterocephalus glaber (naked mole-rat) : Sgpp1 (sphingosine-1-phosphate phosphatase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1275,714,249 - 75,735,729 (-)EnsemblGRCm38mm10GRCm38
GRCm381275,714,248 - 75,735,729 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371276,815,235 - 76,836,716 (-)NCBIGRCm37mm9NCBIm37
MGSCv361276,633,105 - 76,654,502 (-)NCBImm8
Celera1276,819,194 - 76,840,277 (-)NCBICelera
Cytogenetic Map12 C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Sgpp1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552921
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.