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Gene: Tmco1 (transmembrane and coiled-coil domains 1) Mus musculus
Symbol: Tmco1
Name: transmembrane and coiled-coil domains 1
Description: Predicted to have calcium channel activity. Involved in calcium ion transmembrane transport and endoplasmic reticulum calcium ion homeostasis. Predicted to localize to endoplasmic reticulum and integral component of endoplasmic reticulum membrane. Is expressed in clavicle; mandible; maxilla; and rib. Orthologous to human TMCO1 (transmembrane and coiled-coil domains 1); INTERACTS WITH 2,3',4,4',5-Pentachlorobiphenyl; copper atom; copper(0).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1190006A08Rik; 4930403O06Rik; AA109065; AU022572; calcium load-activated calcium channel; CLAC channel; ESTM39; transmembrane and coiled-coil domain-containing protein 1
Homo sapiens (human) : TMCO1 (transmembrane and coiled-coil domains 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tmco1 (transmembrane and coiled-coil domains 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmco1 (transmembrane and coiled-coil domains 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TMCO1 (transmembrane and coiled-coil domains 1)
Canis lupus familiaris (dog) : TMCO1 (transmembrane and coiled-coil domains 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmco1 (transmembrane and coiled-coil domains 1)
Sus scrofa (pig) : TMCO1 (transmembrane and coiled-coil domains 1)
Chlorocebus sabaeus (African green monkey) : TMCO1 (transmembrane and coiled-coil domains 1)
Heterocephalus glaber (naked mole-rat) : Tmco1 (transmembrane and coiled-coil domains 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1167,308,378 - 167,333,978 (+)EnsemblGRCm38mm10GRCm38
GRCm381167,308,670 - 167,333,978 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371169,238,801 - 169,264,109 (+)NCBIGRCm37mm9NCBIm37
MGSCv361169,145,345 - 169,170,653 (+)NCBImm8
Celera1169,726,087 - 169,751,228 (+)NCBICelera
Cytogenetic Map1H2.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tmco1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1552997
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.