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Gene: Pcsk6 (proprotein convertase subtilisin/kexin type 6) Mus musculus
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Symbol: Pcsk6
Name: proprotein convertase subtilisin/kexin type 6
Description: Predicted to have heparin binding activity; nerve growth factor binding activity; and serine-type endopeptidase activity. Involved in determination of left/right symmetry; protein processing; and zygotic determination of anterior/posterior axis, embryo. Predicted to localize to several cellular components, including the cell surface; collagen-containing extracellular matrix; and extracellular space. Is expressed in several structures, including alimentary system; central nervous system; craniocervical region bone; genitourinary system; and limb. Orthologous to human PCSK6 (proprotein convertase subtilisin/kexin type 6); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: b2b2830Clo; C86343; Pace4; paired basic amino acid cleaving system 4; SPC4
Orthologs:
Homo sapiens (human) : PCSK6 (proprotein convertase subtilisin/kexin type 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pcsk6 (proprotein convertase subtilisin/kexin type 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pcsk6 (proprotein convertase subtilisin/kexin type 6)
Pan paniscus (bonobo/pygmy chimpanzee) : PCSK6 (proprotein convertase subtilisin/kexin type 6)
Canis lupus familiaris (dog) : PCSK6 (proprotein convertase subtilisin/kexin type 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pcsk6 (proprotein convertase subtilisin/kexin type 6)
Sus scrofa (pig) : PCSK6 (proprotein convertase subtilisin/kexin type 6)
Chlorocebus sabaeus (African green monkey) : PCSK6 (proprotein convertase subtilisin/kexin type 6)
Heterocephalus glaber (naked mole-rat) : Pcsk6 (proprotein convertase subtilisin/kexin type 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl765,861,734 - 66,050,386 (+)Ensembl
GRCm38765,862,136 - 66,050,386 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37773,007,022 - 73,195,272 (+)NCBIGRCm37mm9NCBIm37
MGSCv36765,740,684 - 65,929,336 (+)NCBImm8
Celera763,292,677 - 63,485,752 (+)NCBICelera
Cytogenetic Map7 CNCBI
cM Map735.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pcsk6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553015
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.