Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Pcsk6 (proprotein convertase subtilisin/kexin type 6) Mus musculus
Symbol: Pcsk6
Name: proprotein convertase subtilisin/kexin type 6
Description: Predicted to have heparin binding activity; nerve growth factor binding activity; and serine-type endopeptidase activity. Involved in determination of left/right symmetry; protein processing; and zygotic determination of anterior/posterior axis, embryo. Predicted to localize to several cellular components, including the cell surface; collagen-containing extracellular matrix; and extracellular space. Is expressed in several structures, including alimentary system; central nervous system; craniocervical region bone; genitourinary system; and limb. Orthologous to human PCSK6 (proprotein convertase subtilisin/kexin type 6); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: b2b2830Clo; C86343; Pace4; paired basic amino acid cleaving system 4; SPC4
Homo sapiens (human) : PCSK6 (proprotein convertase subtilisin/kexin type 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pcsk6 (proprotein convertase subtilisin/kexin type 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pcsk6 (proprotein convertase subtilisin/kexin type 6)
Pan paniscus (bonobo/pygmy chimpanzee) : PCSK6 (proprotein convertase subtilisin/kexin type 6)
Canis lupus familiaris (dog) : PCSK6 (proprotein convertase subtilisin/kexin type 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pcsk6 (proprotein convertase subtilisin/kexin type 6)
Sus scrofa (pig) : PCSK6 (proprotein convertase subtilisin/kexin type 6)
Chlorocebus sabaeus (African green monkey) : PCSK6 (proprotein convertase subtilisin/kexin type 6)
Heterocephalus glaber (naked mole-rat) : Pcsk6 (proprotein convertase subtilisin/kexin type 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl765,861,734 - 66,050,386 (+)Ensembl
GRCm38765,862,136 - 66,050,386 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37773,007,022 - 73,195,272 (+)NCBIGRCm37mm9NCBIm37
MGSCv36765,740,684 - 65,929,336 (+)NCBImm8
Celera763,292,677 - 63,485,752 (+)NCBICelera
Cytogenetic Map7 CNCBI
cM Map735.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pcsk6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553015
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.