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Gene: Ppid (peptidylprolyl isomerase D (cyclophilin D)) Mus musculus
Symbol: Ppid
Name: peptidylprolyl isomerase D (cyclophilin D)
Description: Predicted to have several functions, including Hsp90 protein binding activity; cyclosporin A binding activity; and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in several processes, including cellular response to UV-A; protein peptidyl-prolyl isomerization; and protein refolding. Predicted to localize to the cytosol; mitochondrion; and nuclear lumen. Is expressed in embryo. Orthologous to human PPID (peptidylprolyl isomerase D); PARTICIPATES IN estrogen signaling pathway; Huntington's disease pathway; Parkinson's disease pathway; INTERACTS WITH 17beta-estradiol; 1H-pyrazole; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 40 kDa peptidyl-prolyl cis-trans isomerase; 4930564J03Rik; cyclophilin 40; cyclophilin-40; CYP-40; cytoplasmic cyclophilin D; peptidyl-prolyl cis-trans isomerase D; peptidylprolyl isomerase D-like; PPIase D; Ppidl; Ppif; rotamase D
Homo sapiens (human) : PPID (peptidylprolyl isomerase D)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ppid (peptidylprolyl isomerase D)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppid (peptidylprolyl isomerase D)
Pan paniscus (bonobo/pygmy chimpanzee) : PPID (peptidylprolyl isomerase D)
Canis lupus familiaris (dog) : PPID (peptidylprolyl isomerase D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppid (peptidylprolyl isomerase D)
Sus scrofa (pig) : PPID (peptidylprolyl isomerase D)
more info ...
Related Pseudogenes: Gm11349   Gm13313   Gm18864   Gm18891   Gm18902   Gm5551   Gm6236  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
NCBI Annotation Information: Note: This gene encodes a 370 aa protein that is found in the cytoplasm. In some databases, it has been labeled incorrectly as 'cyclophilin D'. This same name has also been applied to a different protein, found in the mitochondrion, which is represented by Entrez GeneID 105675, Ppif. [09 Apr 2019]
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl379,591,342 - 79,603,650 (+)Ensembl
GRCm38379,591,337 - 79,603,810 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37379,395,311 - 79,407,572 (+)NCBIGRCm37mm9NCBIm37
MGSCv36379,677,316 - 79,689,577 (+)NCBImm8
Celera379,629,272 - 79,641,797 (+)NCBICelera
Cytogenetic Map3 E3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ppid
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553037
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-12-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.