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Gene: Numa1 (nuclear mitotic apparatus protein 1) Mus musculus
Symbol: Numa1
Name: nuclear mitotic apparatus protein 1
CRRD ID: 1553045
Description: Predicted to have several functions, including disordered domain specific binding activity; dynein complex binding activity; and microtubule binding activity. Involved in several processes, including establishment of mitotic spindle orientation; positive regulation of BMP signaling pathway; and positive regulation of epidermis development. Localizes to several cellular components, including lateral cell cortex; mitotic spindle pole; and nuclear matrix. Is expressed in lung epithelium; midbrain ventricular layer; olfactory lobe; pigmented retinal epithelium; and telencephalon ventricular layer. Human ortholog(s) of this gene implicated in acute promyelocytic leukemia. Orthologous to human NUMA1 (nuclear mitotic apparatus protein 1); INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6720401E04Rik; AA764025; AL022610; AU014979; Nu; NuMA
Homo sapiens (human) : NUMA1 (nuclear mitotic apparatus protein 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Numa1 (nuclear mitotic apparatus protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Numa1 (nuclear mitotic apparatus protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NUMA1 (nuclear mitotic apparatus protein 1)
Canis lupus familiaris (dog) : NUMA1 (nuclear mitotic apparatus protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Numa1 (nuclear mitotic apparatus protein 1)
Sus scrofa (pig) : NUMA1 (nuclear mitotic apparatus protein 1)
Chlorocebus sabaeus (African green monkey) : NUMA1 (nuclear mitotic apparatus protein 1)
Heterocephalus glaber (naked mole-rat) : Numa1 (nuclear mitotic apparatus protein 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm397101,583,169 - 101,664,166 (+)NCBI
GRCm387101,933,977 - 102,014,959 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7101,934,111 - 102,014,964 (+)EnsemblGRCm38mm10GRCm38
MGSCv377109,118,357 - 109,163,473 (+)NCBIGRCm37mm9NCBIm37
MGSCv367101,843,664 - 101,888,780 (+)NCBImm8
Celera7102,345,277 - 102,389,657 (+)NCBICelera
Cytogenetic Map7E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Numa1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553045
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.