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Gene: Numa1 (nuclear mitotic apparatus protein 1) Mus musculus
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Symbol: Numa1
Name: nuclear mitotic apparatus protein 1
CRRD ID: 1553045
Description: Predicted to have several functions, including disordered domain specific binding activity; dynein complex binding activity; and microtubule binding activity. Involved in several processes, including establishment of mitotic spindle orientation; positive regulation of BMP signaling pathway; and positive regulation of epidermis development. Localizes to several cellular components, including lateral cell cortex; mitotic spindle pole; and nuclear matrix. Is expressed in lung epithelium; midbrain ventricular layer; olfactory lobe; pigmented retinal epithelium; and telencephalon ventricular layer. Human ortholog(s) of this gene implicated in acute promyelocytic leukemia. Orthologous to human NUMA1 (nuclear mitotic apparatus protein 1); INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6720401E04Rik; AA764025; AL022610; AU014979; Nu; NuMA
Orthologs:
Homo sapiens (human) : NUMA1 (nuclear mitotic apparatus protein 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Numa1 (nuclear mitotic apparatus protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Numa1 (nuclear mitotic apparatus protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NUMA1 (nuclear mitotic apparatus protein 1)
Canis lupus familiaris (dog) : NUMA1 (nuclear mitotic apparatus protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Numa1 (nuclear mitotic apparatus protein 1)
Sus scrofa (pig) : NUMA1 (nuclear mitotic apparatus protein 1)
Chlorocebus sabaeus (African green monkey) : NUMA1 (nuclear mitotic apparatus protein 1)
Heterocephalus glaber (naked mole-rat) : Numa1 (nuclear mitotic apparatus protein 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397101,583,169 - 101,664,166 (+)NCBI
GRCm387101,933,977 - 102,014,959 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7101,934,111 - 102,014,964 (+)EnsemblGRCm38mm10GRCm38
MGSCv377109,118,357 - 109,163,473 (+)NCBIGRCm37mm9NCBIm37
MGSCv367101,843,664 - 101,888,780 (+)NCBImm8
Celera7102,345,277 - 102,389,657 (+)NCBICelera
Cytogenetic Map7E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Numa1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553045
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.