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Gene: Mto1 (mitochondrial tRNA translation optimization 1) Mus musculus
Symbol: Mto1
Name: mitochondrial tRNA translation optimization 1
Description: Predicted to have flavin adenine dinucleotide binding activity. Involved in mitochondrial tRNA wobble uridine modification. Localizes to the mitochondrion. Used to study combined oxidative phosphorylation deficiency. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency. Orthologous to human MTO1 (mitochondrial tRNA translation optimization 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310039H01Rik; 5730419A02Rik; mitochondrial translation optimization 1 homolog; protein MTO1 homolog, mitochondrial
Homo sapiens (human) : MTO1 (mitochondrial tRNA translation optimization 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mto1 (mitochondrial tRNA translation optimization 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mto1 (mitochondrial tRNA translation optimization 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MTO1 (mitochondrial tRNA translation optimization 1)
Canis lupus familiaris (dog) : MTO1 (mitochondrial tRNA translation optimization 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mto1 (mitochondrial tRNA translation optimization 1)
Sus scrofa (pig) : MTO1 (mitochondrial tRNA translation optimization 1)
Chlorocebus sabaeus (green monkey) : MTO1 (mitochondrial tRNA translation optimization 1)
Heterocephalus glaber (naked mole-rat) : Mto1 (mitochondrial tRNA translation optimization 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl978,448,208 - 78,475,348 (+)Ensembl
GRCm38978,443,479 - 78,474,165 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37978,296,017 - 78,321,959 (+)NCBIGRCm37mm9NCBIm37
MGSCv36978,233,904 - 78,259,836 (+)NCBImm8
Celera975,626,365 - 75,652,703 (+)NCBICelera
Cytogenetic Map9 E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Mto1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553062
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.