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Gene: Sipa1 (signal-induced proliferation associated gene 1) Mus musculus
Symbol: Sipa1
Name: signal-induced proliferation associated gene 1
Description: Predicted to have protein C-terminus binding activity. Involved in regulation of cell cycle. Predicted to localize to the protein-containing complex and transport vesicle. Used to study chronic myeloid leukemia. Is expressed in several structures, including genitourinary system; heart; immune system; liver; and lung. Orthologous to human SIPA1 (signal-induced proliferation-associated 1); PARTICIPATES IN platelet-derived growth factor signaling pathway; vasopressin signaling pathway; vasopressin signaling pathway via receptor type 2; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; cadmium dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GTPase-activating protein Spa-1; KIAA4074; signal-induced proliferation-associated protein 1; sipa-1; Spa1
Homo sapiens (human) : SIPA1 (signal-induced proliferation-associated 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sipa1 (signal-induced proliferation-associated 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sipa1 (signal-induced proliferation-associated 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SIPA1 (signal-induced proliferation-associated 1)
Canis lupus familiaris (dog) : SIPA1 (signal-induced proliferation-associated 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sipa1 (signal-induced proliferation-associated 1)
Sus scrofa (pig) : SIPA1 (signal-induced proliferation-associated 1)
Chlorocebus sabaeus (green monkey) : SIPA1 (signal-induced proliferation-associated 1)
Heterocephalus glaber (naked mole-rat) : Sipa1 (signal-induced proliferation-associated 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl195,651,185 - 5,663,707 (-)Ensembl
GRCm38195,651,185 - 5,663,722 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37195,651,185 - 5,663,707 (-)NCBIGRCm37mm9NCBIm37
MGSCv36195,651,194 - 5,663,620 (-)NCBImm8
Celera195,520,784 - 5,533,298 (-)NCBICelera
Cytogenetic Map19 ANCBI
cM Map194.34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Sipa1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553084
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.