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Gene: Sipa1 (signal-induced proliferation associated gene 1) Mus musculus
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Symbol: Sipa1
Name: signal-induced proliferation associated gene 1
Description: Predicted to have protein C-terminus binding activity. Involved in regulation of cell cycle. Predicted to localize to the protein-containing complex and transport vesicle. Used to study chronic myeloid leukemia. Is expressed in several structures, including genitourinary system; heart; immune system; liver; and lung. Orthologous to human SIPA1 (signal-induced proliferation-associated 1); PARTICIPATES IN platelet-derived growth factor signaling pathway; vasopressin signaling pathway; vasopressin signaling pathway via receptor type 2; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; cadmium dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GTPase-activating protein Spa-1; KIAA4074; signal-induced proliferation-associated protein 1; sipa-1; Spa1
Orthologs:
Homo sapiens (human) : SIPA1 (signal-induced proliferation-associated 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sipa1 (signal-induced proliferation-associated 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sipa1 (signal-induced proliferation-associated 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SIPA1 (signal-induced proliferation-associated 1)
Canis lupus familiaris (dog) : SIPA1 (signal-induced proliferation-associated 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sipa1 (signal-induced proliferation-associated 1)
Sus scrofa (pig) : SIPA1 (signal-induced proliferation-associated 1)
Chlorocebus sabaeus (green monkey) : SIPA1 (signal-induced proliferation-associated 1)
Heterocephalus glaber (naked mole-rat) : Sipa1 (signal-induced proliferation-associated 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl195,651,185 - 5,663,707 (-)Ensembl
GRCm38195,651,185 - 5,663,722 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37195,651,185 - 5,663,707 (-)NCBIGRCm37mm9NCBIm37
MGSCv36195,651,194 - 5,663,620 (-)NCBImm8
Celera195,520,784 - 5,533,298 (-)NCBICelera
Cytogenetic Map19 ANCBI
cM Map194.34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Sipa1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553084
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.