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Gene: Nfkbiz (nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta) Mus musculus
Symbol: Nfkbiz
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
Description: Involved in T cell receptor signaling pathway; inflammatory response; and positive regulation of T-helper 17 cell differentiation. Localizes to nucleus. Is expressed in early conceptus; eye; and genitourinary system. Used to study Stevens-Johnson syndrome and atopic dermatitis. Orthologous to human NFKBIZ (NFKB inhibitor zeta); INTERACTS WITH 1,1-dichloroethene; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA408868; I-kappa-B-zeta; IkappaB-zeta; ikappaBzeta; ikB-zeta; IL-1 inducible nuclear ankyrin-repeat protein; INAP; Mail; molecule possessing ankyrin repeats induced by lipopolysaccharide; molecule possessing ankyrin-repeats induced by lipopolysaccharide; NF-kappa-B inhibitor zeta; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
Homo sapiens (human) : NFKBIZ (NFKB inhibitor zeta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nfkbiz (NFKB inhibitor zeta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfkbiz (NFKB inhibitor zeta)
Pan paniscus (bonobo/pygmy chimpanzee) : NFKBIZ (NFKB inhibitor zeta)
Canis lupus familiaris (dog) : NFKBIZ (NFKB inhibitor zeta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfkbiz (NFKB inhibitor zeta)
Sus scrofa (pig) : NFKBIZ (NFKB inhibitor zeta)
Chlorocebus sabaeus (African green monkey) : NFKBIZ (NFKB inhibitor zeta)
Heterocephalus glaber (naked mole-rat) : Nfkbiz (NFKB inhibitor zeta)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1655,811,375 - 55,838,899 (-)EnsemblGRCm38mm10GRCm38
GRCm381655,811,375 - 55,838,954 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371655,811,490 - 55,838,754 (-)NCBIGRCm37mm9NCBIm37
MGSCv361655,736,329 - 55,763,805 (-)NCBImm8
Celera1656,126,905 - 56,154,128 (-)NCBICelera
Cytogenetic Map16C1.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Nfkbiz
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553089
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.