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Gene: Spink4 (serine peptidase inhibitor, Kazal type 4) Mus musculus
Symbol: Spink4
Name: serine peptidase inhibitor, Kazal type 4
Description: Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of peptidase activity. Predicted to localize to the extracellular region. Is expressed in brain ventricular layer; ganglia; liver lobe; and olfactory epithelium. Orthologous to human SPINK4 (serine peptidase inhibitor Kazal type 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; Benzo[k]fluoranthene; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MPGC60; peptide PEC-60 homolog; serine protease inhibitor Kazal-type 4; serine protease inhibitor, Kazal type 4
Homo sapiens (human) : SPINK4 (serine peptidase inhibitor Kazal type 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Spink4 (serine peptidase inhibitor, Kazal type 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spink4 (serine peptidase inhibitor Kazal type 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SPINK4 (serine peptidase inhibitor Kazal type 4)
Canis lupus familiaris (dog) : SPINK4 (serine peptidase inhibitor Kazal type 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spink4 (serine peptidase inhibitor Kazal type 4)
Sus scrofa (pig) : SPINK4 (serine peptidase inhibitor Kazal type 4)
Chlorocebus sabaeus (African green monkey) : SPINK4 (serine peptidase inhibitor Kazal type 4)
Heterocephalus glaber (naked mole-rat) : Spink4 (serine peptidase inhibitor Kazal type 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl440,920,052 - 40,931,395 (+)EnsemblGRCm38mm10GRCm38
GRCm38440,920,056 - 40,931,395 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37440,867,089 - 40,878,428 (+)NCBIGRCm37mm9NCBIm37
MGSCv36441,095,937 - 41,143,924 (+)NCBImm8
Celera440,580,572 - 40,591,997 (+)NCBICelera
Cytogenetic Map4A5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Spink4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553095
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.