Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Fbxw11 (F-box and WD-40 domain protein 11) Mus musculus
Analyze
Symbol: Fbxw11
Name: F-box and WD-40 domain protein 11
Description: Exhibits ubiquitin-protein transferase activity. Contributes to ubiquitin protein ligase activity. Involved in several processes, including cellular protein metabolic process; negative regulation of NIK/NF-kappaB signaling; and positive regulation of circadian rhythm. Localizes to the SCF ubiquitin ligase complex; cytosol; and nucleus. Is expressed in cap mesenchyme; early tubule; ovary; and testis. Orthologous to human FBXW11 (F-box and WD repeat domain containing 11); PARTICIPATES IN Hedgehog signaling pathway; mTOR signaling pathway; vascular endothelial growth factor signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 5-aza-2'-deoxycytidine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310065A07Rik; AA536858; BTRC2; BTRCP2; F-box and WD repeats protein beta-TrCP2; F-box and WD-40 domain protein 1B; F-box/WD repeat-containing protein 11; F-box/WD repeat-containing protein 1B; Fbxw1b; homologous to Slimb protein; HOS; mKIAA0696
Orthologs:
Homo sapiens (human) : FBXW11 (F-box and WD repeat domain containing 11)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fbxw11 (F-box and WD repeat domain containing 11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxw11 (F-box and WD repeat domain containing 11)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXW11 (F-box and WD repeat domain containing 11)
Canis lupus familiaris (dog) : FBXW11 (F-box and WD repeat domain containing 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxw11 (F-box and WD repeat domain containing 11)
Sus scrofa (pig) : FBXW11 (F-box and WD repeat domain containing 11)
Chlorocebus sabaeus (African green monkey) : FBXW11 (F-box and WD repeat domain containing 11)
Heterocephalus glaber (naked mole-rat) : Fbxw11 (F-box and WD repeat domain containing 11)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1132,642,724 - 32,746,816 (+)EnsemblGRCm38mm10GRCm38
GRCm381132,642,555 - 32,746,816 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371132,542,875 - 32,646,816 (+)NCBIGRCm37mm9NCBIm37
MGSCv361132,542,875 - 32,646,816 (+)NCBImm8
Celera1135,061,584 - 35,164,258 (+)NCBICelera
Cytogenetic Map11A4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Cell Lines
Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fbxw11
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553129
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-03-04
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.