Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Casp7 (caspase 7) Mus musculus
Analyze
Symbol: Casp7
Name: caspase 7
Description: Exhibits aspartic-type endopeptidase activity and cysteine-type endopeptidase activity involved in apoptotic process. Involved in several processes, including execution phase of apoptosis; neuron apoptotic process; and response to UV. Predicted to localize to cytosol and nucleus. Is expressed in brain; foregut; olfactory epithelium; and urinary system. Human ortholog(s) of this gene implicated in Alzheimer's disease; breast cancer; colon cancer; and lung non-small cell carcinoma. Orthologous to human CASP7 (caspase 7); PARTICIPATES IN extrinsic apoptotic pathway; FasL mediated signaling pathway; glutathione metabolic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-hydroxy-5alpha-androstan-3-one; 1H-pyrazole.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI314680; apoptotic protease Mch-3; CASP-7; caspase-7; CMH-1; cysteine protease LICE2; ICE-IAP3; mCASP-7; Mch3
Orthologs:
Homo sapiens (human) : CASP7 (caspase 7)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Casp7 (caspase 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Casp7 (caspase 7)
Pan paniscus (bonobo/pygmy chimpanzee) : CASP7 (caspase 7)
Canis lupus familiaris (dog) : CASP7 (caspase 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Casp7 (caspase 7)
Sus scrofa (pig) : CASP7 (caspase 7)
Chlorocebus sabaeus (African green monkey) : CASP7 (caspase 7)
Heterocephalus glaber (naked mole-rat) : Casp7 (caspase 7)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1956,397,129 - 56,442,344 (+)EnsemblGRCm38mm10GRCm38
GRCm381956,396,833 - 56,442,348 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371956,471,619 - 56,516,834 (+)NCBIGRCm37mm9NCBIm37
MGSCv361956,450,379 - 56,495,594 (+)NCBImm8
Celera1958,584,433 - 58,629,610 (+)NCBICelera
Cytogenetic Map19D2NCBI
cM Map1951.84NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Casp7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553182
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.