Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Casp7 (caspase 7) Mus musculus
Symbol: Casp7
Name: caspase 7
Description: Exhibits aspartic-type endopeptidase activity and cysteine-type endopeptidase activity involved in apoptotic process. Involved in several processes, including execution phase of apoptosis; neuron apoptotic process; and response to UV. Predicted to localize to cytosol and nucleus. Is expressed in brain; foregut; olfactory epithelium; and urinary system. Human ortholog(s) of this gene implicated in Alzheimer's disease; breast cancer; colon cancer; and lung non-small cell carcinoma. Orthologous to human CASP7 (caspase 7); PARTICIPATES IN extrinsic apoptotic pathway; FasL mediated signaling pathway; glutathione metabolic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-hydroxy-5alpha-androstan-3-one; 1H-pyrazole.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI314680; apoptotic protease Mch-3; CASP-7; caspase-7; CMH-1; cysteine protease LICE2; ICE-IAP3; mCASP-7; Mch3
Homo sapiens (human) : CASP7 (caspase 7)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Casp7 (caspase 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Casp7 (caspase 7)
Pan paniscus (bonobo/pygmy chimpanzee) : CASP7 (caspase 7)
Canis lupus familiaris (dog) : CASP7 (caspase 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Casp7 (caspase 7)
Sus scrofa (pig) : CASP7 (caspase 7)
Chlorocebus sabaeus (African green monkey) : CASP7 (caspase 7)
Heterocephalus glaber (naked mole-rat) : Casp7 (caspase 7)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1956,397,129 - 56,442,344 (+)EnsemblGRCm38mm10GRCm38
GRCm381956,396,833 - 56,442,348 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371956,471,619 - 56,516,834 (+)NCBIGRCm37mm9NCBIm37
MGSCv361956,450,379 - 56,495,594 (+)NCBImm8
Celera1958,584,433 - 58,629,610 (+)NCBICelera
Cytogenetic Map19D2NCBI
cM Map1951.84NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Casp7
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553182
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.