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Gene: Nectin2 (nectin cell adhesion molecule 2) Mus musculus
Symbol: Nectin2
Name: nectin cell adhesion molecule 2
Description: Exhibits cell adhesion molecule binding activity and protein homodimerization activity. Involved in several processes, including homophilic cell adhesion via plasma membrane adhesion molecules; sperm mitochondrion organization; and spermatid development. Localizes to the cell-cell contact zone; plasma membrane; and zonula adherens. Human ortholog(s) of this gene implicated in Alzheimer's disease and multiple sclerosis. Is expressed in brain; cochlea; male reproductive system; molar enamel organ; and primitive collecting duct. Orthologous to human NECTIN2 (nectin cell adhesion molecule 2); PARTICIPATES IN E-cadherin signaling pathway; INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI325026; AI987993; Cd112; herpes virus entry mediator B; herpesvirus entry mediator B; hveB; mHveB; MPH; murine herpes virus entry protein B; murine herpesvirus entry protein B; nectin-2; poliovirus receptor homolog; poliovirus receptor-related 2; poliovirus receptor-related protein 2; poliovirus sensitivity; Pvr; Pvrl2; Pvs
Homo sapiens (human) : NECTIN2 (nectin cell adhesion molecule 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nectin2 (nectin cell adhesion molecule 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nectin2 (nectin cell adhesion molecule 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NECTIN2 (nectin cell adhesion molecule 2)
Canis lupus familiaris (dog) : NECTIN2 (nectin cell adhesion molecule 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nectin2 (nectin cell adhesion molecule 2)
Sus scrofa (pig) : NECTIN2 (nectin cell adhesion molecule 2)
Chlorocebus sabaeus (African green monkey) : NECTIN2 (nectin cell adhesion molecule 2)
Heterocephalus glaber (naked mole-rat) : Nectin2 (nectin cell adhesion molecule 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl719,716,644 - 19,750,483 (-)EnsemblGRCm38mm10GRCm38
GRCm38719,716,644 - 19,749,573 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37720,301,993 - 20,334,922 (-)NCBIGRCm37mm9NCBIm37
MGSCv36718,875,183 - 18,907,991 (-)NCBImm8
Celera717,122,731 - 17,155,753 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Nectin2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553240
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.