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Gene: Nectin2 (nectin cell adhesion molecule 2) Mus musculus
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Symbol: Nectin2
Name: nectin cell adhesion molecule 2
Description: Exhibits cell adhesion molecule binding activity and protein homodimerization activity. Involved in several processes, including homophilic cell adhesion via plasma membrane adhesion molecules; sperm mitochondrion organization; and spermatid development. Localizes to the cell-cell contact zone; plasma membrane; and zonula adherens. Human ortholog(s) of this gene implicated in Alzheimer's disease and multiple sclerosis. Is expressed in brain; cochlea; male reproductive system; molar enamel organ; and primitive collecting duct. Orthologous to human NECTIN2 (nectin cell adhesion molecule 2); PARTICIPATES IN E-cadherin signaling pathway; INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI325026; AI987993; Cd112; herpes virus entry mediator B; herpesvirus entry mediator B; hveB; mHveB; MPH; murine herpes virus entry protein B; murine herpesvirus entry protein B; nectin-2; poliovirus receptor homolog; poliovirus receptor-related 2; poliovirus receptor-related protein 2; poliovirus sensitivity; Pvr; Pvrl2; Pvs
Orthologs:
Homo sapiens (human) : NECTIN2 (nectin cell adhesion molecule 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nectin2 (nectin cell adhesion molecule 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nectin2 (nectin cell adhesion molecule 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NECTIN2 (nectin cell adhesion molecule 2)
Canis lupus familiaris (dog) : NECTIN2 (nectin cell adhesion molecule 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nectin2 (nectin cell adhesion molecule 2)
Sus scrofa (pig) : NECTIN2 (nectin cell adhesion molecule 2)
Chlorocebus sabaeus (African green monkey) : NECTIN2 (nectin cell adhesion molecule 2)
Heterocephalus glaber (naked mole-rat) : Nectin2 (nectin cell adhesion molecule 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl719,716,644 - 19,750,483 (-)EnsemblGRCm38mm10GRCm38
GRCm38719,716,644 - 19,749,573 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37720,301,993 - 20,334,922 (-)NCBIGRCm37mm9NCBIm37
MGSCv36718,875,183 - 18,907,991 (-)NCBImm8
Celera717,122,731 - 17,155,753 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

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Nomenclature History
 
More on Nectin2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553240
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.