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Gene: Skp1 (S-phase kinase-associated protein 1) Mus musculus
Symbol: Skp1
Name: S-phase kinase-associated protein 1
Description: Predicted to contribute to ubiquitin protein ligase activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Localizes to centrosome; cullin-RING ubiquitin ligase complex; and cytosol. Predicted to colocalize with PcG protein complex. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; notochord; and sensory organ. Orthologous to human SKP1 (S-phase kinase associated protein 1); PARTICIPATES IN Notch signaling pathway; nuclear factor kappa B signaling pathway; nuclear factor, erythroid 2 like 2 signaling pathway; INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine (ortholog); acrylamide (ortholog); bisphenol F (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 15kDa; 2610043E24Rik; 2610206H23Rik; cyclin A/CDK2-associated protein p19; cyclin-A/CDK2-associated protein p19; EMC19; OCP-II; OCP2; p19A; p19Skp1; S-phase kinase-associated protein 1A; Skp1a; Tceb1l; transcription elongation factor B (SIII), polypeptide 1 (15 kDa),-like; transcription elongation factor B (SIII), polypeptide 1-like
Homo sapiens (human) : SKP1 (S-phase kinase associated protein 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Skp1 (S-phase kinase-associated protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Skp1 (S-phase kinase associated protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SKP1 (S-phase kinase associated protein 1)
Canis lupus familiaris (dog) : SKP1 (S-phase kinase associated protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Skp1 (S-phase kinase associated protein 1)
Sus scrofa (pig) : SKP1 (S-phase kinase associated protein 1)
Chlorocebus sabaeus (African green monkey) : SKP1 (S-phase kinase associated protein 1)
Heterocephalus glaber (naked mole-rat) : Skp1 (S-phase kinase associated protein 1)
more info ...
Related Pseudogenes: Gm12988  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1152,231,995 - 52,246,858 (+)EnsemblGRCm38mm10GRCm38
GRCm381152,230,522 - 52,246,858 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371152,045,497 - 52,060,360 (+)NCBIGRCm37mm9NCBIm37
MGSCv361152,075,432 - 52,090,281 (+)NCBImm8
Celera1156,801,165 - 56,816,028 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.86NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Skp1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553334
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.