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Gene: Sel1l (sel-1 suppressor of lin-12-like (C. elegans)) Mus musculus
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Symbol: Sel1l
Name: sel-1 suppressor of lin-12-like (C. elegans)
Description: Predicted to contribute to ubiquitin-protein transferase activity. Involved in ERAD pathway; protein secretion; and triglyceride metabolic process. Predicted to localize to the Derlin-1 retrotranslocation complex and Hrd1p ubiquitin ligase ERAD-L complex. Human ortholog(s) of this gene implicated in pancreatic cancer. Is expressed in several structures, including genitourinary system; liver; neural tube; pancreas parenchyma; and spleen. Orthologous to human SEL1L (SEL1L adaptor subunit of ERAD E3 ubiquitin ligase); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW493766; KIAA4137; mKIAA4137; protein sel-1 homolog 1; sel-1L; Sel1 (suppressor of lin-12) 1 homolog; Sel1h; suppressor of lin-12-like protein 1
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1291,806,043 - 91,849,157 (-)EnsemblGRCm38mm10GRCm38
GRCm381291,806,043 - 91,849,157 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371293,044,483 - 93,087,597 (-)NCBIGRCm37mm9NCBIm37
MGSCv361292,211,600 - 92,254,714 (-)NCBImm8
Celera1293,107,703 - 93,150,124 (-)NCBICelera
Cytogenetic Map12D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Sel1l
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553402
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.