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Gene: Masp2 (mannan-binding lectin serine peptidase 2) Mus musculus
Symbol: Masp2
Name: mannan-binding lectin serine peptidase 2
Description: Predicted to have calcium-dependent protein binding activity; complement component C4b binding activity; and serine-type endopeptidase activity. Involved in complement activation, lectin pathway. Predicted to localize to the extracellular space. Is expressed in several structures, including brain and liver. Orthologous to human MASP2 (mannan binding lectin serine peptidase 2); PARTICIPATES IN coagulation cascade pathway; complement system pathway; Staphylococcus aureus infection pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: mannan-binding lectin serine protease 2; mannose-binding protein-associated serine protease 2; MAp19; MASP-2; MBL-associated serine protease 2
Homo sapiens (human) : MASP2 (mannan binding lectin serine peptidase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Masp2 (mannan-binding lectin serine peptidase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Masp2 (mannan binding lectin serine peptidase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MASP2 (mannan binding lectin serine peptidase 2)
Canis lupus familiaris (dog) : MASP2 (mannan binding lectin serine peptidase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Masp2 (mannan binding lectin serine peptidase 2)
Sus scrofa (pig) : MASP2 (mannan binding lectin serine peptidase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm384148,594,622 - 148,615,499 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374147,976,653 - 147,989,591 (+)NCBIGRCm37mm9NCBIm37
MGSCv364147,446,346 - 147,459,282 (+)NCBImm8
Celera4150,863,826 - 150,876,764 (+)NCBICelera
Cytogenetic Map4 E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Masp2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553528
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.