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Gene: Hcrtr2 (hypocretin (orexin) receptor 2) Mus musculus
Symbol: Hcrtr2
Name: hypocretin (orexin) receptor 2
Description: Exhibits orexin receptor activity. Involved in phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to localize to the integral component of plasma membrane. Used to study narcolepsy. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Orthologous to human HCRTR2 (hypocretin receptor 2); PARTICIPATES IN G protein mediated signaling pathway via Galphai family; G protein mediated signaling pathway via Galphaq family; orexin/hypocretin signaling pathway via orexin/hypocretin receptor 2; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; milnacipran; N-methyl-4-phenylpyridinium.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hypocretin receptor type 2; mOX2aR; mOX2bR; mOXR2; orexin receptor type 2; orexin receptor type-2a; ox-2-R; ox2-R; OX2aR; OX2bR; OX2R; OXR2
Homo sapiens (human) : HCRTR2 (hypocretin receptor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hcrtr2 (hypocretin receptor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hcrtr2 (hypocretin receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HCRTR2 (hypocretin receptor 2)
Canis lupus familiaris (dog) : HCRTR2 (hypocretin receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hcrtr2 (hypocretin receptor 2)
Sus scrofa (pig) : HCRTR2 (hypocretin receptor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38976,225,880 - 76,323,623 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37976,073,687 - 76,171,385 (-)NCBIGRCm37mm9NCBIm37
MGSCv36976,011,789 - 76,109,487 (-)NCBImm8
Celera973,390,040 - 73,487,756 (-)NCBICelera
Cytogenetic Map9 DNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hcrtr2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553616
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.