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Gene: Srsf2 (serine and arginine-rich splicing factor 2) Mus musculus
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Symbol: Srsf2
Name: serine and arginine-rich splicing factor 2
CRRD ID: 1553658
Description: Exhibits pre-mRNA binding activity. Involved in regulation of alternative mRNA splicing, via spliceosome. Localizes to nuclear speck and spliceosomal complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and retina. Used to study myelodysplastic syndrome. Human ortholog(s) of this gene implicated in acute myeloid leukemia and myelodysplastic syndrome. Orthologous to human SRSF2 (serine and arginine rich splicing factor 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: D11Wsu175; D11Wsu175e; MRF-; MRF-1; myelin regulatory factor 1; Pr264; putative myelin regulatory factor 1; SC3; SC35; serine/arginine-rich splicing factor 2; Sf; Sfr; Sfrs10; Sfrs2; splicing component, 35 kDa; splicing factor Sc35; splicing factor, arginine/serine-rich 2; splicing factor, arginine/serine-rich 2 (SC-35)
Orthologs:
Homo sapiens (human) : SRSF2 (serine and arginine rich splicing factor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Srsf2 (serine and arginine rich splicing factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Srsf2 (serine and arginine rich splicing factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SRSF2 (serine and arginine rich splicing factor 2)
Canis lupus familiaris (dog) : SRSF2 (serine and arginine rich splicing factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Srsf2 (serine and arginine rich splicing factor 2)
Sus scrofa (pig) : SRSF2 (serine and arginine rich splicing factor 2)
Chlorocebus sabaeus (African green monkey) : SRSF2 (serine and arginine rich splicing factor 2)
Heterocephalus glaber (naked mole-rat) : Srsf2 (serine and arginine rich splicing factor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl11116,849,901 - 116,853,094 (-)EnsemblGRCm38mm10GRCm38
GRCm3811116,849,897 - 116,853,675 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711116,711,211 - 116,714,408 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611116,665,997 - 116,669,172 (-)NCBImm8
Celera11128,590,379 - 128,593,569 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1181.49NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Srsf2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553658
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.